Chemistry:Butonitazene

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Short description: Chemical compound
Butonitazene
Butonitazine.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC24H32N4O3
Molar mass424.545 g·mol−1
3D model (JSmol)

Butonitazene is a benzimidazole derivative with opioid effects, which has been sold over the internet as a designer drug. It has relatively low potency compared to many related compounds, and has generally been encountered as a component of mixtures with other substances rather than in its pure form. However, it is still several times the potency of morphine and has been implicated in several cases of drug overdose.[1][2][3] Butonitazene is a Schedule I drug in the USA, along with several related compounds.[4]

See also

References

  1. "Intoxications in an Australian Emergency Department Involving 'Nitazene' Benzylbenzimidazole Synthetic Opioids (Etodesnitazene, Butonitazene and Protonitazene)". Journal of Analytical Toxicology 47 (1): e6–e9. August 2022. doi:10.1093/jat/bkac062. PMID 35983900. 
  2. "Acute Intoxications and Fatalities Associated With Benzimidazole Opioid (Nitazene Analog) Use: A Systematic Review". Therapeutic Drug Monitoring 44 (4): 494–510. August 2022. doi:10.1097/FTD.0000000000000970. PMID 35149665. 
  3. "A Forward-Thinking Approach to Addressing the New Synthetic Opioid 2-Benzylbenzimidazole Nitazene Analogs by Liquid Chromatography-Tandem Quadrupole Mass Spectrometry (LC-QQQ-MS)". Journal of Analytical Toxicology 46 (3): 221–231. March 2022. doi:10.1093/jat/bkab117. PMID 34792157. 
  4. "21 CFR Part 1308. [Docket No. DEA–900 Schedules of Controlled Substances: Temporary Placement of Butonitazene, Etodesnitazene, Flunitazene, Metodesnitazene, Metonitazene, N-Pyrrolidino etonitazene, and Protonitazene in Schedule I."]. Federal Register (Drug Enforcement Administration) 87 (70): 21556. 12 April 2022. https://www.govinfo.gov/content/pkg/FR-2022-04-12/pdf/2022-07640.pdf.