Biology:NCR2
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Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene.[1][2] NCR2 has also been designated as CD336 (cluster of differentiation 336), NKp44, NKP44; NK-p44, LY95, and dJ149M18.1.[3]
References
- ↑ "NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily". J Exp Med 189 (5): 787–96. Jun 1999. doi:10.1084/jem.189.5.787. PMID 10049942.
- ↑ "Entrez Gene: NCR2 natural cytotoxicity triggering receptor 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9436.
- ↑ "NCR2 natural cytotoxicity triggering receptor 2 [Homo sapiens (human)] - Gene - NCBI". https://www.ncbi.nlm.nih.gov/gene/9436.
Further reading
- "Characterization of the recognition of tumor cells by the natural cytotoxicity receptor, NKp44.". Biochemistry 46 (25): 7426–36. 2007. doi:10.1021/bi7000455. PMID 17536787.
- "Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D.". J. Immunol. 175 (8): 5463–70. 2005. doi:10.4049/jimmunol.175.8.5463. PMID 16210654.
- "Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44.". Blood 106 (6): 2076–82. 2005. doi:10.1182/blood-2004-12-4802. PMID 15941912.
- "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors.". J. Immunol. 174 (5): 2653–60. 2005. doi:10.4049/jimmunol.174.5.2653. PMID 15728472.
- "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.". Blood 105 (9): 3615–22. 2005. doi:10.1182/blood-2004-07-2585. PMID 15657183.
- "NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence.". J. Immunol. 172 (2): 899–906. 2004. doi:10.4049/jimmunol.172.2.899. PMID 14707061.
- "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity.". Structure 11 (6): 725–34. 2004. doi:10.1016/S0969-2126(03)00095-9. PMID 12791260.
- "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells.". Eur. J. Immunol. 33 (5): 1235–41. 2003. doi:10.1002/eji.200323896. PMID 12731048.
- "The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44.". Eur. J. Immunol. 33 (2): 567–77. 2003. doi:10.1002/immu.200310033. PMID 12645956.
- "Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44.". Acta Crystallogr. D 58 (Pt 10 Pt 2): 1843–5. 2003. doi:10.1107/S0907444902012325. PMID 12351833.
External links
- NCR2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Natural cytotoxicity triggering receptor 2 (NCR2)
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