Chemistry:O-774

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Short description: Chemical compound
O-774
O-774 Structure.svg
Identifiers
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC25H35NO2
Molar mass381.560 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)

O-774 is a classical cannabinoid derivative which acts as a potent agonist for the cannabinoid receptors, with a Ki of 0.6 nM at CB1, and very potent cannabinoid effects in animal studies.[1][2]

See also

References

  1. "Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol". Journal of Medicinal Chemistry 41 (22): 4400–7. October 1998. doi:10.1021/jm9803875. PMID 9784115. 
  2. "Cannabinoid Receptor Ligands and Structure-Activity Relationships.". The Cannabinoid Receptors. Part I.. Humana Press. 2009. pp. 6–9. ISBN 978-1-58829-712-9.