Chemistry:O-1238
From HandWiki
Short description: Chemical compound
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| Formula | C22H29N3O2 |
| Molar mass | 367.493 g·mol−1 |
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O-1238 is a drug which is a cannabinoid derivative that is used in scientific research. It is a partial agonist at the cannabinoid receptor CB1,[1] producing a maximal stimulation of 58.3%[2] with a Ki of 8.45nM.[3]
References
- ↑ "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British Journal of Pharmacology 128 (3): 684–8. October 1999. doi:10.1038/sj.bjp.0702806. PMID 10516649.
- ↑ "An investigation into the structural determinants of cannabinoid receptor ligand efficacy". British Journal of Pharmacology 126 (7): 1575–84. April 1999. doi:10.1038/sj.bjp.0702469. PMID 10323589.
- ↑ "Structural determinants of the partial agonist-inverse agonist properties of 6'-azidohex-2'-yne-delta8-tetrahydrocannabinol at cannabinoid receptors". British Journal of Pharmacology 128 (3): 735–43. October 1999. doi:10.1038/sj.bjp.0702836. PMID 10516656.
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