Chemistry:HU-345

From HandWiki
Short description: Chemical compound
HU-345
HU-345 Structure.svg
Identifiers
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC21H24O3
Molar mass324.420 g·mol−1
3D model (JSmol)
  (verify)

HU-345 (cannabinol quinone) is a drug that is able to inhibit aortic ring angiogenesis more potently than its parent compound cannabinol (CBN).[1][2] It exhibits no psychoactive effects on the body.

HU-345 can be derived through the oxidative degradation of CBN.[3]

See also

References

  1. "A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells". Molecular Pharmacology 70 (1): 51–59. July 2006. doi:10.1124/mol.105.021089. PMID 16571653. 
  2. US patent 0092584, Mechoulam R, Kogan NM, Rabinowitz R, Schlesinger M, "Therapeutic Use of Quinonoid Derivatives of Cannabinoids", granted 2011-04-21 
  3. "Cannabinoid Quinones-A Review and Novel Observations". Molecules 26 (6): 1761. March 2021. doi:10.3390/molecules26061761. PMID 33801057.