Chemistry:PTI-2

From HandWiki
Short description: Chemical compound
PTI-2
PTI-2 structure.png
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaC23H33N3OS
Molar mass399.60 g·mol−1
3D model (JSmol)

PTI-2 (SGT-49) is an indole-based synthetic cannabinoid.[1] It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-1. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.[2][3][4]

See also

References

  1. "PTI-2". Cayman Chemical. https://www.caymanchem.com/app/template/Product.vm/catalog/9001950. 
  2. Adam-Worrall J, Morrison AJ, Wishart G, Kiyoi T, McArthur DR, "(Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor.", US patent 7700634, issued 20 April 2010, assigned to Organon NV
  3. Paul David Ratcliffe PD, Adam-Worrall J, Morrison AJ, Francis SJ, Kiyoi T, "Indole Derivatives", US patent 7763732, issued 27 July 2010, assigned to Organon NV
  4. "Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists". Bioorganic & Medicinal Chemistry Letters 21 (6): 1748–53. March 2011. doi:10.1016/j.bmcl.2011.01.082. PMID 21316962.