Chemistry:NE-CHMIMO

From HandWiki
Short description: Chemical compound
NE-CHMIMO
NE-CHMIMO.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC26H25NO
Molar mass367.492 g·mol−1
3D model (JSmol)

NE-CHMIMO (CHM-018) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1][2][3] NE-CHMIMO is the 1-cyclohexylmethyl (instead of 1-pentyl) analogue of the first-generation synthetic cannabinoid JWH-018. The corresponding cyclohexylmethyl derivative of JWH-081 had also been reported several months earlier.[4]

Legal status

In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as NE-CHMIMO are Schedule I Controlled Substances.[5]

NE-CHMIMO is a controlled substance in Japan as of November 2019.[6]

See also

References

  1. "Separation and structural characterization of the new synthetic cannabinoid JWH-018 cyclohexyl methyl derivative "NE-CHMIMO" using flash chromatography, GC-MS, IR and NMR spectroscopy". Forensic Science International 266: e93–e98. September 2016. doi:10.1016/j.forsciint.2016.05.031. PMID 27297324. 
  2. "Synthetic cannabinoids in hair - Pragmatic approach for method updates, compound prevalences and concentration ranges in authentic hair samples". Analytica Chimica Acta 1006: 61–73. May 2018. doi:10.1016/j.aca.2017.12.029. PMID 30016265. 
  3. "NE-CHMIMO". New Synthetic Drugs Database. http://nsddb.eu/substance/576/. 
  4. "Identification of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) and other designer drugs in herbal incense". Forensic Science International 260: 40–53. March 2016. doi:10.1016/j.forsciint.2015.12.001. PMID 26795397. 
  5. 21 U.S.C. § 812: Schedules of controlled substances
  6. "指定薬物を指定する省令が公布されました|厚生労働省". Ministry of Health, Labour and Welfare. https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/oshirase/20191114-1.html.