Chemistry:HU-336
From HandWiki
Short description: Chemical compound
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| Formula | C21H28O3 |
| Molar mass | 328.452 g·mol−1 |
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HU-336 is a strongly antiangiogenic compound, significantly inhibiting angiogenesis at concentrations as low as 300 nM. It inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of pro- and antiangiogenic cytokines and their receptors. HU-336 is highly effective against tumor xenografts in nude mice. Although it is technically the oxidized quinone of delta-8 THC, it is entirely non psychoactive.[1]
See also
References
- ↑ "A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells". Molecular Pharmacology 70 (1): 51–9. July 2006. doi:10.1124/mol.105.021089. PMID 16571653.
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