Chemistry:JWH-167
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| Preferred IUPAC name
1-(1-Pentyl-1H-indol-3-yl)-2-phenylethan-1-one | |
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| Properties | |
| C21H23NO | |
| Molar mass | 305.421 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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Tracking categories (test):
JWH-167 (1-pentyl-3-(phenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 1.75 times selectivity for CB1 with a Ki of 90 nM ± 17 and 159 nM ± 14 at CB2. Similar to the related 2'-methoxy compound JWH-250, and the 2'-chloro compound JWH-203, JWH-167 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.[1][2]
In the United States, CB1 receptor agonists of the 3-phenylacetylindole class such as JWH-167 are Schedule I Controlled Substances.[3]
References
- ↑ "1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles". Bioorganic & Medicinal Chemistry Letters 15 (18): 4110–3. September 2005. doi:10.1016/j.bmcl.2005.06.008. PMID 16005223.
- ↑ "Indoles and related compounds as cannabinoid ligands". Mini Reviews in Medicinal Chemistry 8 (4): 370–87. April 2008. doi:10.2174/138955708783955935. PMID 18473928.
- ↑ : Schedules of controlled substances
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