Chemistry:Desmethylsibutramine
From HandWiki
Short description: Chemical compound
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| Formula | C16H24ClN |
| Molar mass | 265.83 g·mol−1 |
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Desmethylsibutramine (Norsibutramine, BTS-54354) is an active metabolite of the anorectic drug sibutramine. It is a more potent monoamine reuptake inhibitor than sibutramine and has been sold as an ingredient in weight loss products sold as dietary supplements, along with related compounds such as the N-ethyl and 3,4-dichloro derivatives.[1][2][3][4][5]
See also
References
- ↑ "Enantioselective behavioral effects of sibutramine metabolites". European Journal of Pharmacology 397 (1): 93–102. May 2000. doi:10.1016/s0014-2999(00)00216-8. PMID 10844103.
- ↑ "Determination of PDE-5 inhibitors and appetite suppressants in adulterated dietary supplements using LC/PDA and LC/MS". Food Additives & Contaminants. Part B, Surveillance 5 (1): 29–32. 2012. doi:10.1080/19393210.2012.656706. PMID 24779692.
- ↑ "Active pharmaceutical ingredients detected in herbal food supplements for weight loss sampled on the Dutch market". Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment 31 (11): 1783–1793. 2014. doi:10.1080/19440049.2014.958574. PMID 25247833.
- ↑ "Analysis of 40 weight loss compounds adulterated in health supplements by liquid chromatography quadrupole linear ion trap mass spectrometry". Drug Testing and Analysis 8 (3–4): 351–6. 2016. doi:10.1002/dta.1846. PMID 26305055.
- ↑ "Metabolic analysis of the illegal analogues of anti-obesity drugs using LC-Q-TOF-MS/MS". Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 1163: 122502. January 2021. doi:10.1016/j.jchromb.2020.122502. PMID 33412503.
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