Chemistry:Panuramine

Panuramine
Clinical data
ATC code	None;
Identifiers
	IUPAC name N-{[1-(naphthalen-2-ylmethyl)piperidin-4-yl]carbamoyl}benzamide;
CAS Number	80349-58-2 ; 80349-03-7 (HCl);
PubChem CID	72002;
ChemSpider	65002;
UNII	1UWS3T8EAB;
Chemical and physical data
Formula	C24H25N3O2
Molar mass	387.483 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1ccccc1)NC(=O)NC4CCN(Cc2ccc3c(c2)cccc3)CC4;

Short description: Chemical compound

Panuramine (Wy-26,002) is an antidepressant which was synthesized in 1981 by Wyeth.^[1] It acts as a potent and selective serotonin reuptake inhibitor (SSRI).^[2] It was never marketed.^[1]

References

↑ ^1.0 ^1.1 David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9. https://books.google.com/books?id=A0THacd46ZsC&q=panuramine&pg=PA1519.
↑ "Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine in the brain of the rat". Neuropharmacology 23 (9): 1049–52. September 1984. doi:10.1016/0028-3908(84)90127-8. PMID 6514142.

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Clinical data

ATC code	None
Identifiers
IUPAC name N-{[1-(naphthalen-2-ylmethyl)piperidin-4-yl]carbamoyl}benzamide
CAS Number	80349-58-2 80349-03-7 (HCl)
PubChem CID	72002
ChemSpider	65002
UNII	1UWS3T8EAB
Chemical and physical data
Formula	C₂₄H₂₅N₃O₂
Molar mass	387.483 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(c1ccccc1)NC(=O)NC4CCN(Cc2ccc3c(c2)cccc3)CC4