Chemistry:Didesmethylcitalopram

Short description: Chemical compound

Didesmethylcitalopram

Clinical data
ATC code	none
Legal status
Legal status	In general: uncontrolled
Pharmacokinetic data
Elimination half-life	100 h
Identifiers
IUPAC name (RS or S)-1-[3-aminopropyl]-1- (4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number	62498-69-5 Y
ChemSpider	23935928 N
UNII	ZE9YVI4ZEE
Chemical and physical data
Formula	C18H17FN2O
Molar mass	296.345 g·mol−1
3D model (JSmol)	Interactive image
SMILES c1cc(ccc1[C@]2(c3ccc(cc3CO2)C#N)CCCN)F
InChI InChI=1S/C18H17FN2O/c19-16-5-3-15(4-6-16)18(8-1-9-20)17-7-2-13(11-21)10-14(17)12-22-18/h2-7,10H,1,8-9,12,20H2/t18-/m0/s1 N Key:RKUKMUWCRLRPEJ-SFHVURJKSA-N N
NY (what is this?)  (verify)

Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic). Didesmethylescitalopram is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.

See also

• Desmethylcitalopram
• Desmethylsertraline
• Desmethylvenlafaxine
• Norfluoxetine