Chemistry:California Proposition 65 list of chemicals

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Short description: Chemicals regulated in the United States

The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of January 3, 2020.[1] As a result of lawsuits, the list also contains substances known only to cause cancer in animals.[2]

This list is not exhaustive, as the complete list contains over 900 chemicals.[2]

Chemicals currently listed under California Proposition 65

Current Proposition 65 list
Substance CAS Registry Number
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 26148-68-5
1,4-Dichloro-2-nitrobenzene 89-61-2
p-chloro-α,α,α-trifluorotoluene (para-Chlorobenzotrifluoride, PCBTF) 98-56-6
Bevacizumab 216974-75-3
Aflatoxins
Ceramic fibers
Certain combined chemotherapy for lymphomas
para-Nitroanisole 100-17-4
2,4-Dichloro-1-nitrobenzene 611-06-3
Δ9-Tetrahydrocannabinol (Δ9-THC)
2-Chloronitrobenzene 88-73-3
2-Amino-4-chlorophenol 95-85-2
Cannabis (marijuana) smoke
Abiraterone acetate 154229-18-2
Acetaldehyde 75-07-0
Acetamide 60-35-5
Acetazolamide 59-66-5
Acetochlor 34256-82-1
Acetohydroxamic acid 546-88-3
2-Acetylaminofluorene 53-96-3
Acifluorfen sodium 62476-59-9
Acrylamide 79-06-1
Acrylonitrile 107-13-1
Actinomycin D 50-76-0
AF-2 ([2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide) 3688-53-7
Alachlor 15972-60-8
Alcoholic beverages
Aldrin 309-00-2
All-trans retinoic acid 302-79-4
Aloe vera, non-decolorized whole leaf extract
Alprazolam 28981-97-7
Altretamine 645-05-6
Amantadine hydrochloride 665-66-7
Amikacin sulfate 39831-55-5
2-Aminoanthraquinone 117-79-3
p-Aminoazobenzene 60-09-3
o-Aminoazotoluene 97-56-3
4-Aminobiphenyl (4-amino-diphenyl) 92-67-1
1-Amino-2,4-dibromoanthraquinone 81-49-2
3-Amino-9-ethylcarbazole hydrochloride 6109-97-3
2-Aminofluorene 153-78-6
Aminoglutethimide 125-84-8
Aminoglycosides
1-Amino-2-methylanthraquinone (Disperse Orange 11) 82-28-0
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 712-68-5
4-Amino-2-nitrophenol 119-34-6
Aminopterin 54-62-6
Amiodarone hydrochloride 19774-82-4
Amitraz 33089-61-1
Amitrole 61-82-5
Amoxapine 14028-44-5
Amsacrine 51264-14-3
Anabolic steroids
Androstenedione 63-05-8
ACE inhibitors
Aniline 62-53-3
Aniline hydrochloride 142-04-1
o-Anisidine 90-04-0
o-Anisidine hydrochloride 134-29-2
Anisindione 117-37-3
Anthraquinone 84-65-1
Antimony oxide (Antimony trioxide) 1309-64-4
Aramite 140-57-8
Areca nut
Aristolochic acids
Arsenic (inorganic arsenic compounds)
Arsenic (inorganic oxides)
Asbestos 1332-21-4
Aspirin during the last three months of pregnancy 50-78-2
Atenolol 29122-68-7
Atrazine 1912-24-9
Auramine 492-80-8
Auranofin 34031-32-8
Avermectin B1 (Abamectin) 71751-41-2
Azacitidine 320-67-2
Azaserine 115-02-6
Azathioprine 446-86-6
Azobenzene 103-33-3
Barbiturates
Beclomethasone dipropionate 5534-09-8
Benomyl 17804-35-2
Benthiavalicarb-isopropyl 177406-68-7
Benz[a]anthracene 56-55-3
Benzene 71-43-2
Benzidine (and its salts) 92-87-5
Benzidine-based dyes
Benzodiazepines
Benzo[b]fluoranthene 205-99-2
Benzo[j]fluoranthene 205-82-3
Benzo[k]fluoranthene 207-08-9
Benzofuran 271-89-6
Benzophenone 119-61-9
Benzo[a]pyrene 50-32-8
Benzotrichloride 98-07-7
Benzphetamine hydrochloride 5411-22-3
Benzyl chloride 100-44-7
Benzyl violet 4B 1694-09-3
Beryllium and beryllium compounds
Betel quid with tobacco
Betel quid without tobacco
2,2-Bis(bromomethyl)-1,3-propanediol 3296-90-0
Bis(2-chloroethyl)ether 111-44-4
N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) 494-03-1
Bischloroethyl nitrosourea (BCNU, Carmustine) 154-93-8
Bis(chloromethyl)ether 542-88-1
Bis(2-chloro-1-methylethyl)ether
Bisphenol A (BPA) 80-05-7
Bitumen
Bracken fern
Bromacil lithium salt 53404-19-6
Bromate 15541-45-4
Bromochloroacetic acid 5589-96-8
Bromodichloroacetic acid 71133-14-7
Bromodichloromethane 75-27-4
Bromoethane 74-96-4
Bromoform 75-25-2
1-Bromopropane (1-BP) 106-94-5
2-Bromopropane (2-BP) 75-26-3
Bromoxynil 1689-84-5
Bromoxynil octanoate 1689-99-2
Butabarbital sodium 143-81-7
1,3-Butadiene 106-99-0
1,4-Butanediol dimethanesulfonate (Busulfan) 55-98-1
Butylated hydroxyanisole 25013-16-5
Butyl benzyl phthalate (BBP) 85-68-7
beta-Butyrolactone 3068-88-0
Cacodylic acid 75-60-5
Cadmium and cadmium compounds
Caffeic acid 331-39-5
Captafol 2425-06-1
Captan 133-06-2
Carbamazepine 298-46-4
Carbaryl 63-25-2
Carbazole 86-74-8
Carbon black 1333-86-4
Carbon disulfide 75-15-0
Carbon monoxide 630-08-0
Carbon tetrachloride 56-23-5
Carboplatin 41575-94-4
N-Carboxymethyl-N-nitrosourea 60391-92-6
Catechol 120-80-9
Chenodiol 474-25-9
Chloral 75-87-6
Chloral hydrate 302-17-0
Chlorambucil 305-03-3
Chloramphenicol sodium succinate 982-57-0
Chlorcyclizine hydrochloride 1620-21-9
Chlordane 57-74-9
Chlordecone (Kepone) 143-50-0
Chlordiazepoxide 58-25-3
Chlordiazepoxide hydrochloride 438-41-5
Chlordimeform 6164-98-3
Chlorendic acid 115-28-6
Chlorinated paraffins (Avg. chain length C12; approx. 60 percent chlorine by weight) 108171-26-2
p-Chloroaniline 106-47-8
p-Chloroaniline hydrochloride 20265-96-7
Chloroethane 75-00-3
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, Lomustine) 13010-47-4
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) 13909-09-6
Chloroform 67-66-3
Chloromethyl methyl ether 107-30-2
3-Chloro-2-methylpropene 563-47-3
1-Chloro-4-nitrobenzene 100-00-5
4-Chloro-o-phenylenediamine 95-83-0
Chloroprene 126-99-8
2-Chloropropionic acid 598-78-7
Chlorothalonil 1897-45-6
p-Chloro-o-toluidine 95-69-2
Strong acid salts of p-Chloro-o-toluidine
5-Chloro-o-toluidine and its strong acid salts 95-79-4
Chlorotrianisene 569-57-3
Chlorozotocin 54749-90-5
Chlorpyrifos 2921-88-2
Chrysene 218-01-9
C.I. Acid Red 114 6459-94-5
C.I. Basic Red 9 monohydrochloride 569-61-9
C.I. Direct Blue 15 2429-74-5
C.I. Direct Blue 218 28407-37-6
C.I. Disperse Yellow 3 2832-40-8
C.I. Solvent Yellow 14 842-07-9
Ciclosporin (Cyclosporine, Cyclosporine A) 59865-13-3; 79217-60-0
Cidofovir 113852-37-2
Cinnamyl anthranilate 87-29-6
Cisplatin 15663-27-1
Citrus Red No. 2 6358-53-8
Cladribine 4291-63-8
Clarithromycin 81103-11-9
Clobetasol propionate 25122-46-7
Clofibrate 637-07-0
Clomiphene citrate 50-41-9
Clorazepate dipotassium 57109-90-7
CMNP (pyrazachlor) 6814-58-0
Cobalt metal powder 7440-48-4
Cobalt(II) oxide 1307-96-6
Cobalt sulfate 10124-43-3
Cobalt sulfate heptahydrate 10026-24-1
Cocaine 50-36-2
Cocamide diethanolamine (Coconut oil diethanolamine condensate)
Codeine phosphate 52-28-8
Coke oven emissions
Colchicine 64-86-8
Conjugated estrogens
Creosotes
p-Cresidine 120-71-8
Cumene 98-82-8
Cupferron 135-20-6
Cyanazine 21725-46-2
Cycasin 14901-08-7
Cycloate 1134-23-2
Cycloheximide 66-81-9
Cyclopenta[cd]pyrene 27208-37-3
Cyclophosphamide 50-18-0; 6055-19-2
Cyhexatin 13121-70-5
Cytarabine 147-94-4
Cytembena 21739-91-3
D&C Orange No. 17 3468-63-1
D&C Red No. 8 2092-56-0
D&C Red No. 9 5160-02-1
D&C Red No. 19 81-88-9
Dacarbazine 4342-03-4
Daminozide 1596-84-5
Danazol 17230-88-5
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) 117-10-2
Daunomycin 20830-81-3
Daunorubicin hydrochloride 23541-50-6
2,4-D butyric acid 94-82-6
DDD (Dichlorodiphenyl-dichloroethane) 72-54-8
DDE (Dichlorodiphenyl-dichloroethylene) 72-55-9
DDT (Dichlorodiphenyl-trichloroethane) 50-29-3
o,p'-DDT 789-02-6
p,p'-DDT 50-29-3
DDVP (Dichlorvos) 62-73-7
Demeclocycline hydrochloride 64-73-3
Des-ethyl atrazine (DEA) 6190-65-4
Des-isopropyl atrazine (DIA) 1007-28-9
N,N'-Diacetylbenzidine 613-35-4
2,4-Diaminoanisole 615-05-4
2,4-Diaminoanisole sulfate 39156-41-7
2,4-Diamino-6-chloro-s-triazine (DACT) 3397-62-4
4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) 101-80-4
2,4-Diaminotoluene 95-80-7
Diazepam 439-14-5
Diazoaminobenzene 136-35-6
Diazoxide 364-98-7
Dibenz[a,h]acridine 226-36-8
Dibenz[a,j]acridine 224-42-0
Dibenzanthracenes
Dibenz[a,c]anthracene 215-58-7
Dibenz[a,h]anthracene 53-70-3
Dibenz[a,j]anthracene 224-41-9
7H-Dibenzo[c,g]carbazole 194-59-2
Dibenzo[a,e]pyrene 192-65-4
Dibenzo[a,h]pyrene 189-64-0
Dibenzo[a,i]pyrene 189-55-9
Dibenzo[a,l]pyrene 191-30-0
Dibromoacetic acid 631-64-1
Dibromoacetonitrile 3252-43-5
1,2-Dibromo-3-chloropropane (DBCP) 96-12-8
2,3-Dibromo-1-propanol 96-13-9
Dichloroacetic acid 79-43-6
p-Dichlorobenzene 106-46-7
3,3'-Dichlorobenzidine 91-94-1
3,3'-Dichlorobenzidine dihydrochloride 612-83-9
1,4-Dichloro-2-butene 764-41-0
3,3'-Dichloro-4,4'-diamino-diphenyl ether 28434-86-8
1,1-Dichloroethane 75-34-3
Dichloromethane (Methylene chloride) 75-09-2
Dichlorophene 97-23-4
Dichlorphenamide 120-97-8
1,2-Dichloropropane 78-87-5
1,3-Dichloro-2-propanol (1,3-DCP) 96-23-1
1,3-Dichloropropene 542-75-6
Diclofop methyl 51338-27-3
Dicumarol 66-76-2
Dieldrin 60-57-1
Diepoxybutane 1464-53-5
Diesel engine exhaust
Diethanolamine 111-42-2
Di(2-ethylhexyl)phthalate (DEHP) 117-81-7
1,2-Diethylhydrazine 1615-80-1
Diethylstilbestrol (DES) 56-53-1
Diethyl sulfate 64-67-5
Diflunisal 22494-42-4
Diglycidyl resorcinol ether (DGRE) 101-90-6
Dihydroergotamine mesylate 6190-39-2
Dihydrosafrole 94-58-6
Di-isodecyl phthalate (DIDP) 68515-49-1/ 26761-40-0
Diisononyl phthalate (DINP)
Diisopropyl sulfate 2973-10-6
Diltiazem hydrochloride 33286-22-5
3,3'-Dimethoxybenzidine (o-Dianisidine) 119-90-4
3,3'-Dimethoxybenzidine dihydrochloride 20325-40-0
N,N-Dimethylacetamide 127-19-5
4-Dimethylaminoazobenzene 60-11-7
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole 55738-54-0
7,12-Dimethylbenz[a]anthracene 57-97-6
3,3'-Dimethylbenzidine (ortho-Tolidine) 119-93-7
3,3'-Dimethylbenzidine dihydrochloride 612-82-8
Dimethylcarbamoyl chloride 79-44-7
1,1-Dimethylhydrazine (UDMH) 57-14-7
1,2-Dimethylhydrazine 540-73-8
2,6-Dimethyl-N-nitrosomorpholine (DMNM) 1456-28-6
Dimethyl sulfate 77-78-1
N,N-Dimethyl-p-toluidine 99-97-8
Dimethylvinylchloride 513-37-1
Di-n-butyl phthalate (DBP) 84-74-2
Di-n-hexyl phthalate (DnHP) 84-75-3
m-Dinitrobenzene 99-65-0
o-Dinitrobenzene 528-29-0
p-Dinitrobenzene 100-25-4
3,7-Dinitrofluoranthene 105735-71-5
3,9-Dinitrofluoranthene 22506-53-2
1,3-Dinitropyrene 75321-20-9
1,6-Dinitropyrene 42397-64-8
1,8-Dinitropyrene 42397-65-9
2,4-Dinitrotoluene 121-14-2
2,6-Dinitrotoluene 606-20-2
Dinitrotoluene
Dinocap 39300-45-3
Dinoseb 88-85-7
Di-n-propyl isocinchomeronate (MGK Repellent 326) 136-45-8
1,4-Dioxane 123-91-1
Diphenylhydantoin (Phenytoin) 57-41-0
Diphenylhydantoin sodium salt 630-93-3
Direct Black 38 1937-37-7
Direct Blue 6 2602-46-2
Direct Brown 95 16071-86-6
Disodium cyanodithioimidocarbonate 138-93-2
Disperse Blue 1 2475-45-8
Diuron 330-54-1
Doxorubicin hydrochloride (Adriamycin) 25316-40-9
Doxycycline 564-25-0
Doxycycline calcium 94088-85-4
Doxycycline hyclate 24390-14-5
Doxycycline monohydrate 17086-28-1
Emissions from Combustion of coal
Emissions from high-temperature unrefined rapeseed oil
Endrin 72-20-8
Environmental tobacco smoke (ETS)
Epichlorohydrin 106-89-8
Epoxiconazole 135319-73-2
Ergotamine tartrate 379-79-3
Erionite 12510-42-8; 66733-21-9
Estradiol 50-28-2
Estragole 140-67-0
Estrogens (steroidal)
Estrone 53-16-7
Estropipate 7280-37-7
Ethanol in alcoholic beverages
Ethinylestradiol 57-63-6
Ethionamide 536-33-4
Ethoprop 13194-48-4
Ethyl acrylate 140-88-5
Ethylbenzene 100-41-4
Ethyl dipropylthiocarbamate 759-94-4
Ethyl-4,4'-dichlorobenzilate 510-15-6
Ethylene dibromide 106-93-4
Ethylene dichloride (1,2-Dichloroethane) 107-06-2
Ethylene glycol (when ingested) 107-21-1
Ethylene glycol monoethyl ether 110-80-5
Ethylene glycol monoethyl ether acetate 111-15-9
Ethylene glycol monomethyl ether 109-86-4
Ethylene glycol monomethyl ether acetate 110-49-6
Ethyleneimine (Aziridine) 151-56-4
Ethylene oxide 75-21-8
Ethylene thiourea 96-45-7
Ethyl methanesulfonate 62-50-0
Etodolac 41340-25-4
Etoposide 33419-42-0
Etoposide in combination with Cisplatin and Bleomycin
Etretinate 54350-48-0
Fenoxaprop ethyl 66441-23-4
Fenoxycarb 72490-01-8
Filgrastim 121181-53-1
Fluazifop butyl 69806-50-4
Flunisolide 3385-03-3
Fluorouracil 51-21-8
Fluoxymesterone 76-43-7
Flurazepam hydrochloride 1172-18-5
Flurbiprofen 5104-49-4
Flutamide 13311-84-7
Fluticasone propionate 80474-14-2
Fluvalinate 69409-94-5
Folpet 133-07-3
Formaldehyde (gas) 50-00-0
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole 3570-75-0
Fumonisin B1 116355-83-0
Furan 110-00-9
Furazolidone 67-45-8
Furfuryl alcohol 98-00-0
Furmecyclox 60568-05-0
Fusarin C 79748-81-5
Gallium arsenide 1303-00-0
Ganciclovir 82410-32-0
Ganciclovir sodium 107910-75-8
Gasoline engine exhaust (condensates/extracts)
Gemfibrozil 25812-30-0
Gentian violet(Crystal violet) 548-62-9
Glass wool fibers (when inhalable and biopersistent)
Glu-P-1 (2-Amino-6-methyldipyrido[1,2- a:3',2'-d]imidazole) 67730-11-4
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) 67730-10-3
Glycidaldehyde 765-34-4
Glycidol 556-52-5
Glyphosate 1071-83-6
Goldenseal root powder
Goserelin acetate 65807-02-5
Griseofulvin 126-07-8
Gyromitrin (Acetaldehyde methylformylhydrazone) 16568-02-8
Halazepam 23092-17-3
Halobetasol propionate 66852-54-8
Haloperidol 52-86-8
Halothane 151-67-7
HC Blue 1 2784-94-3
Heptachlor 76-44-8
Heptachlor epoxide 1024-57-3
Herbal remedies containing plant species of the genus Aristolochia
Hexachlorobenzene 118-74-1
Hexachlorobutadiene 87-68-3
Hexachlorocyclohexane
Hexachlorodibenzodioxin 34465-46- 8
Hexachloroethane 67-72-1
2,4-Hexadienal
Hexafluoroacetone 684-16-2
Hexamethylphosphoramide 680-31-9
n-Hexane 110-54-3
2,5-Hexanedione 110-13-4
Hexavalent chromium
Histrelin acetate
Hydramethylnon 67485-29-4
Hydrazine 302-01-2
Hydrazine sulfate 10034-93-2
Hydrazobenzene (1,2-Diphenylhydrazine) 122-66-7
Hydrogen cyanide 74-90-8
1-Hydroxyanthraquinone 129-43-1
Hydroxyurea 127-07-1
Idarubicin hydrochloride 57852-57-0
Ifosfamide 3778-73-2
Iodine-131 10043-66-0
Imazalil 35554-44-0
Indeno[1,2,3-cd]pyrene 193-39-5
Indium phosphide 22398-80-7
Indium tin oxide 50926-11-9
IQ (2-Amino-3-methylimidazo[4,5-f] quinoline) 76180-96-6
Iprodione 36734-19-7
Iprovalicarb 140923-17-7; 140923-25-7
Iron dextran complex 9004-66-4
Isobutyl nitrite 542-56-3
Isoprene 78-79-5
Isopyrazam 881685-58-1
Isotretinoin 4759-48-2
Isoxaflutole 141112-29-0
Kresoxim-methyl 143390-89-0
Lactofen 77501-63-4
Lasiocarpine 303-34-4
Lead 7439-92-1
Lead and lead compounds
Lead acetate 301-04-2
Lead phosphate 7446-27-7
Lead subacetate 1335-32-6
Leather dust
Leuprolide acetate 74381-53-6
Levodopa 59-92-7
Levonorgestrel implants 797-63-7
Lindane and other hexachlorocyclohexane isomers
Linuron 330-55-2
Lithium carbonate 554-13-2
Lithium citrate 919-16-4
Lorazepam 846-49-1
Lovastatin 75330-75-5
Lynestrenol 52-76-6
Malathion 121-75-5
Malonaldehyde, sodium salt 24382-04-5
Mancozeb 8018-01-7
Maneb 12427-38-2
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole) 68006-83-7
Mebendazole 31431-39-7
Medroxyprogesterone acetate 71-58-9
Megestrol acetate 595-33-5
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) 77094-11-2
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) 77500-04-0
Melphalan 148-82-3
Menotropins 9002-68-0
Mepanipyrim 110235-47-7
Meprobamate 57-53-4
2-Mercaptobenzothiazole 149-30-4
Mercaptopurine 6112-76-1
Mercury and compounds
Merphalan 531-76-0
Mestranol 72-33-3
Metam potassium 137-41-7
Methacycline hydrochloride 3963-95-9
Metham sodium 137-42-8
Methanol 67-56-1
Methazole 20354-26-1
Methimazole 60-56-0
Methotrexate 59-05-2
Methotrexate sodium 15475-56-6
5-Methoxypsoralen with ultraviolet A therapy 484-20-8
8-Methoxypsoralen with ultraviolet A therapy 298-81-7
2-Methylaziridine (Propyleneimine) 75-55-8
Methylazoxymethanol 590-96-5
Methylazoxymethanol acetate 592-62-1
Methyl bromide as fumigant 74-83-9
Methyl carbamate 598-55-0
Methyl chloride 74-87-3
3-Methylcholanthrene 56-49-5
5-Methylchrysene 3697-24-3
4,4'-Methylene bis(2-chloroaniline) 101-14-4
4,4'-Methylene bis(N,N-dimethyl)benzenamine 101-61-1
4,4'-Methylene bis(2-methylaniline) 838-88-0
4,4'-Methylenedianiline 101-77-9
4,4'-Methylenedianiline dihydrochloride 13552-44-8
Methyleugenol 93-15-2
2-Methylimidazole 693-98-1
4-Methylimidazole 822-36-6
Methyl iodide 74-88-4
Methyl isobutyl ketone (MIBK) 108-10-1
Methyl isocyanate (MIC) 624-83-9
Methyl mercury and compounds
Methyl methanesulfonate 66-27-3
Methyl-n-butyl ketone 591-78-6
2-Methyl-1-nitroanthraquinone 129-15-7
N-Methyl-N'-nitro-N-nitrosoguanidine 70-25-7
N-Methylolacrylamide 924-42-5
N-Methylpyrrolidone 872-50-4
α-Methyl styrene (alpha-Methylstyrene) 98-83-9
Methyltestosterone 58-18-4
Methylthiouracil 56-04-2
Metiram 9006-42-2
Metronidazole 443-48-1
Michler's ketone 90-94-8
Midazolam hydrochloride 59467-96-8
Minocycline hydrochloride 13614-98-7
Mirex 2385-85-5
Misoprostol 59122-46-2
Mitomycin C 50-07-7
Mitoxantrone hydrochloride 70476-82-3
Molybdenum trioxide 1313-27-5
Molinate 2212-67-1
MON 4660 (dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane) 71526-07-3
MON 13900 (furilazole) 121776-33-8
3-Monochloropropane-1,2-diol (3-MCDP) 96-24-2
Monocrotaline 315-22-0
MOPP (vincristine-prednisone-nitrogen mustard-procarbazine mixture) 113803-47-7
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone 139-91-3
Mustard Gas 505-60-2
MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone) 77439-76-0
Myclobutanil 88671-89-0
Beta-Myrcene 123-35-3
Nabam 142-59-6
Nafarelin acetate 86220-42-0
Nafenopin 3771-19-5
Nalidixic acid 389-08-2
Naphthalene 91-20-3
1-Naphthylamine 134-32-7
2-Naphthylamine 91-59-8
Neomycin sulfate 1405-10-3
Netilmicin sulfate 56391-57-2
Nickel (Metallic) 7440-02-0
Nickel acetate 373-02-4
Nickel carbonate 3333-67-3
Nickel carbonyl 13463-39-3
Nickel (soluble compounds)
Nickel hydroxide 12054-48-7; 12125-56-3
Nickelocene 1271-28-9
Nickel oxide 1313-99-1
Nickel refinery dust from the pyrometallurgical process
Nickel subsulfide 12035-72-2
Nicotine 54-11-5
Nifedipine 21829-25-4
Nimodipine 66085-59-4
Niridazole 61-57-4
Nitrapyrin 1929-82-4
Nitrilotriacetic acid 139-13-9
Nitrilotriacetic acid, trisodium salt monohydrate 18662-53-8
5-Nitroacenaphthene 602-87-9
o-Nitroanisole 91-23-6
Nitrobenzene 98-95-3
4-Nitrobiphenyl 92-93-3
6-Nitrochrysene 7496-02-8
Nitrofen 1836-75-5
2-Nitrofluorene 607-57-8
Nitrofurantoin 67-20-9
Nitrofurazone 59-87-0
1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone 555-84-0
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 531-82-8
Nitrogen mustard (Mechlorethamine) 51-75-2
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) 55-86-7
Nitrogen mustard N-oxide 126-85-2
Nitrogen mustard N-oxide hydrochloride 302-70-5
Nitromethane 75-52-5
2-Nitropropane 79-46-9
1-Nitropyrene 5522-43-0
4-Nitropyrene 57835-92-4
N,N-Dimethylformamide 68-12-2
N-Nitrosodi-n-butylamine 924-16-3
N-Nitrosodiethanolamine 1116-54-7
N-Nitrosodiethylamine 55-18-5
N-Nitrosodimethylamine 62-75-9
p-Nitrosodiphenylamine 156-10-5
N-Nitrosodiphenylamine 86-30-6
N-Nitrosodi-n-propylamine 621-64-7
N-Nitroso-N-ethylurea 759-73-9
N-Nitrosohexamethyleneimine 932-83-2
3-(N-Nitrosmethylamino) propionitrile 60153-49-3
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone 64091-91-4
N-Nitrosomethyl-n-butylamine 7068-83-9
N-Nitrosomethyl-n-decylamine 75881-22-0
N-Nitrosomethyl-n-dodecylamine 55090-44-3
N-Nitrosomethylethylamine 10595-95-6
N-Nitrosomethyl-n-heptylamine 16338-99-1
N-Nitrosomethyl-n-hexylamine 28538-70-7
N-Nitrosomethyl-n-nonylamine 75881-19-5
N-Nitrosomethyl-n-octylamine 34423-54-6
N-Nitrosomethyl-n-pentylamine 13256-07-0
N-Nitrosomethyl-n-propylamine 924-46-9
N-Nitrosomethyl-n-tetradecylamine 75881-20-8
N-Nitrosomethyl-n-undecylamine 68107-26-6
N-Nitroso-N-methylurea 684-93-5
N-Nitroso-N-methylurethane 615-53-2
N-Nitrosomethylvinylamine 4549-40-0
N-Nitrosomorpholine 59-89-2
N-Nitrosonornicotine 16543-55-8
N-Nitrosopiperidine 100-75-4
N-Nitrosopyrrolidine 930-55-2
N-Nitrososarcosine 13256-22-9
o-Nitrotoluene 88-72-2
Nitrous oxide 10024-97-2
Norethisterone (Norethindrone) 68-22-4
Norethisterone acetate (Norethindrone acetate) 51-98-9
Norethynodrel 68-23-5
Norgestrel 6533-00-2
Ochratoxin A 303-47-9
Oil Orange SS 2646-17-5
Oral contraceptives, combined or sequential
Oryzalin 19044-88-3
Oxadiazon 19666-30-9
Oxazepam 604-75-1
Oxydemeton methyl 301-12-2
Oxymetholone 434-07-1
Oxytetracycline 79-57-2
Oxytetracycline hydrochloride 2058-46-0
Oxythioquinox (Chinomethionat) 2439-01-2
Paclitaxel 33069-62-4
Palygorskite fibers (> 5 µm in length) 12174-11-7
Panfuran S 794-93-4
Paramethadione 115-67-3
Parathion 56-38-2
Penicillamine 52-67-5
Pentabromodiphenyl ether mixture [DE-71 (technical grade)]
Pentachlorophenol 87-86-5
Pentachlorophenol and by-products of its synthesis (complex mixture)
Pentobarbital sodium 57-33-0
Pentosan polysulfate sodium
Pentostatin 53910-25-1
Perfluorooctane sulfonate (PFOS) 1763-23-1
Perfluorooctanoic acid (PFOA) 335-67-1
Pertuzumab 380610-27-5
Phenacemide 63-98-9
Phenacetin (in analgesic mixtures) 62-44-2
Phenazopyridine 94-78-0
Phenazopyridine hydrochloride 136-40-3
Phenesterin 3546-10-9
Phenobarbital 50-06-6
Phenolphthalein 77-09-8
Phenoxybenzamine 59-96-1
Phenoxybenzamine hydrochloride 63-92-3
Phenprocoumon 435-97-2
o-Phenylenediamine and its salts 95-54-5
Phenyl glycidyl ether 122-60-1
Phenylhydrazine and its salts
o-Phenylphenate, sodium 132-27-4
o-Phenylphenol 90-43-7
Phenylphosphine 638-21-1
PhiP (2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine) 105650-23-5
Pimozide 2062-78-4
Pioglitazone 111025-46-8
Pipobroman 54-91-1
Pirimicarb 23103-98-2
Plicamycin 18378-89-7
Polybrominated biphenyls
Polychlorinated biphenyls
Polychlorinated biphenyls (containing 60 or more percent chlorine by molecular weight)
Polychlorinated dibenzo-p-dioxins
Polychlorinated dibenzofurans
Polygeenan 53973-98-1
Ponceau MX 3761-53-3
Ponceau 3R 3564-09-8
Potassium bromate 7758-01-2
Potassium dimethyldithiocarbamate 128-03-0
Pravastatin sodium 81131-70-6
Prednisolone sodium phosphate 125-02-0
Primidone 125-33-7
Procarbazine 671-16-9
Procarbazine hydrochloride 366-70-1
Procymidone 32809-16-8
Progesterone 57-83-0
Pronamide 23950-58-5
Propachlor 1918-16-7
1,3-Propane sultone 1120-71-4
Propargite 2312-35-8
Propazine 139-40-2
beta-Propiolactone 57-57-8
Propoxur 114-26-1
Propylene glycol mono-t-butyl ether 57018-52-7
Propylene oxide 75-56-9
Propylthiouracil 51-52-5
Pulegone 89-82-7
Pymetrozine 123312-89-0
Pyridine 110-86-1
Pyrimethamine 58-14-0
Quazepam 36735-22-5
Quinoline and its strong acid salts
Quizalofop-ethyl 76578-14-8
Radionuclides
Reserpine 50-55-5
Residual (heavy) fuel oils
Resmethrin 10453-86-8
Retinol/retinyl esters [refer 1]
Ribavirin 36791-04-5
Riddelliine 23246-96-0
Rifampin 13292-46-1
Safrole 94-59-7
Salted fish, Chinese-style
Secobarbital sodium 309-43-3
Sedaxane 874967-67-6
Selenium sulfide 7446-34-6
Sermorelin acetate
Shale oils 68308-34-9
Silica, crystalline (airborne particles of respirable size)
Simazine 122-34-9
Sodium dimethyldithiocarbamate 128-04-1
Sodium fluoroacetate 62-74-8
Soots, tars, and mineral oils (untreated and mildly treated oils and used engine oils)
Spirodiclofen 148477-71-8
Spironolactone 52-01-7
Stanozolol 10418-03-8
Sterigmatocystin 10048-13-2
Streptomycin sulfate 3810-74-0
Streptozocin (streptozotocin) 18883-66-4
Strong inorganic acid mists containing sulfuric acid
Styrene 100-42-5
Styrene oxide 96-09-3
Sulfallate 95-06-7
Sulfasalazine (Salicylazosulfapyridine) 599-79-1
Sulfur dioxide 7446-09-5
Sulindac 38194-50-2
Talc containing asbestiform fibers
Tamoxifen 10540-29-1
Tamoxifen citrate 54965-24-1
Temazepam 846-50-4
Teniposide 29767-20-2
Terbacil 5902-51-2
Teriparatide 52232-67-4
Terrazole 2593-15-9
Testosterone 58-22-0
Testosterone cypionate 58-20-8
Testosterone enanthate 315-37-7
Tetrabromobisphenol A 79-94-7
3,3',4,4'-Tetrachloroazobenzene 14047-09-7
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 1746-01-6
1,1,1,2-Tetrachloroethane 630-20-6
1,1,2,2-Tetrachloroethane 79-34-5
Tetrachloroethylene (Perchloroethylene) 127-18-4
p-α,α,α-Tetrachlorotoluene 5216-25-1
Tetrachlorvinphos 22248-79-9
Tetracycline 60-54-8
Tetracyclines
Tetracycline hydrochloride 64-75-5
Tetrafluoroethylene 116-14-3
Tetranitromethane 509-14-8
Thalidomide 50-35-1
Thioacetamide 62-55-5
Titanium dioxide 13463-67-7
4,4'-Thiodianiline 139-65-1
Thiodicarb 59669-26-0
Thioguanine 154-42-7
Thiophanate methyl 23564-05-8
2-Thiouracil 141-90-2
Thiourea 62-56-6
Thorium dioxide 1314-20-1
Tobacco, oral use of smokeless products
Tobacco smoke
Tobacco smoke (Primary)
Tobramycin sulfate 49842-07-1
Toluene 108-88-3
Toluene diisocyanate 26471-62-5
o-Toluidine 95-53-4
o-Toluidine hydrochloride 636-21-5
Topiramate 97240-79-4
Toxaphene (Polychlorinated camphenes) 8001-35-2
Fusarium toxins
Treosulfan 299-75-2
Triadimefon 43121-43-3
Triamterene 396-01-0
Triazolam 28911-01-5
S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF) 78-48-8
Tributyltin methacrylate 2155-70-6
Trichlormethine (Trimustine hydrochloride) 817-09-4
Trichloroacetic acid 76-03-9
Trichloroethylene 79-01-6
2,4,6-Trichlorophenol 88-06-2
1,2,3-Trichloropropane 96-18-4
Trientine hydrochloride 38260-01-4
Triforine 26644-46-2
Trilostane 13647-35-3
Trimethadione 127-48-0
2,4,5-Trimethylaniline
Trimethyl phosphate 512-56-1
Trimetrexate glucuronate 82952-64-5
TRIM®VX
2,4,6-Trinitrotoluene (TNT) 118-96-7
Triphenyltin hydroxide 76-87-9
Tris(1-aziridinyl)phosphine sulfide (Thiotepa) 52-24-4
Tris(2-chloroethyl) phosphate 115-96-8
Tris(2,3-dibromopropyl)phosphate 126-72-7
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) 13674-87-8
Trp-P-1 (Tryptophan-P-1) 62450-06-0
Trp-P-2 (Tryptophan-P-2) 62450-07-1
Trypan blue 72-57-1
Unleaded gasoline
Uracil mustard 66-75-1
Urethane (Ethyl carbamate) 51-79-6
Urofollitropin 97048-13-0
Valproate (Valproic acid) 99-66-1
Vanadium pentoxide (only orthorhombic) 1314-62-1
Vinblastine sulfate 143-67-9
Vinclozolin 50471-44-8
Vincristine sulfate 2068-78-2
Vinyl bromide 593-60-2
Vinyl chloride 75-01-4
4-Vinylcyclohexene 100-40-3
4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexenedioxide) 106-87-6
Vinyl fluoride 75-02-5
Vinylidene chloride (1,1-Dichloroethylene) 75-35-4
Vinyl trichloride (1,1,2-Trichloroethane) 79-00-5
Vismodegib 879085-55-9
Warfarin 81-81-2
Wood dust
2,6-Xylidine (2,6-Dimethylaniline) 87-62-7
Zalcitabine 7481-89-2
Zidovudine (AZT) 30516-87-1
Zileuton 111406-87-2

Annotation

  1. When in daily dosages in excess of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/retinyl esters arerequired and essential for maintenance of normal reproductive function. The recommended daily level during pregnancy is 8,000 IU.)

Chemicals that were formerly listed under California Proposition 65

Formerly on Proposition 65 list
Substance CAS Registry Number Date removed
Bisphenol A (BPA) 80-05-7 April 11, 2013
Allyl chloride 107-05-1 October 29, 1999
Phenyl glycidyl ether 122-60-1 April 4, 2014
α-Methyl styrene 98-83-9 April 4, 2014
tert-Amyl methyl ether 994-05-8 December 13, 2013
n-Butyl glycidyl ether 2426-08-6 April 4, 2014
Chloramphenicol 56-75-7 January 4, 2013
Chlorodibromomethane 124-48-1 October 29, 1999
Chlorsulfuron 64902-72-3 June 6, 2014
Cyclohexanol 108-93-0 January 25, 2002
Diaminotoluene (mixed) November 20, 2015
Dienestrol 84-17-3 January 4, 2013
Diglycidyl ether 2238-07-5 April 4, 2014
2,4-DP (dichloroprop) 120-36-5 January 25, 2002
Ethyl-tert-butyl ether 637-92-3 December 13, 2013
2-Ethylhexanoic acid 149-57-5 December 13, 2013
Isosafrole 120-58-1 December 8, 2006
Methyl isopropyl ketone 563-80-4 April 4, 2014
5-Nitro-o-anisidine 99-59-2 December 8, 2006
p,p’-Oxybis(benzenesulfonyl hydrazide) 80-51-3 December 13, 2013
Saccharin 81-07-2 April 6, 2001
Saccharin, sodium 128-44-9 January 17, 2003
para-Toluidine 106-49-0 October 29, 1999
1,3,5-Triglycidyl-s-triazinetrione 2451-62-9 December 13, 2013
Tris(aziridinyl)-p-benzoquinone (Triaziquone) 68-76-8 December 8, 2006
Zineb 12122-67-7 October 29, 1999

Numerical identifier assigned by the Chemical Abstracts Service (CAS)

Comments:

  • Many substances include its strong acid salts
  • Airborne particles of many substances are cancerogenic
  • Several chemical commodities were removed in the last years
  • Bisphenol A (BPA) was removed from the list on April 19, 2013, and was relisted on May 11, 2015.

References

  1. The Proposition 65 List
  2. 2.0 2.1 Mohan, Geoffrey (2020-07-23). "You see the warnings everywhere. But does Prop. 65 really protect you?". Los Angeles Times. https://www.latimes.com/business/story/2020-07-23/prop-65-product-warnings. "Companies in every sector of the consumer economy now routinely attach warnings for any of the more than 900 chemicals and elements covered by Proposition 65,..."