Chemistry:Delta-8-THCM
From HandWiki
Delta-8-THCM (O-Methyl-Δ8-THC) is a chemical compound related to phytocannabinoids found in Cannabis. It has been sold as a designer drug, first identified in Sweden in June 2024.[1] However, it is a known compound which has been well established to almost entirely lack cannabinoid-like effects in mice, rats and monkeys,[2][3] unlike the dimethylheptyl analogue L-759,633 which is a selective agonist for CB2 and has antiinflammatory but not psychoactive effects.[4]
See also
References
- ↑ "European Drug Report 2025 – Full Book". European Union Drugs Agency (euda.europa.eu). 6 June 2025. https://www.euda.europa.eu/system/files/documents/2025-06/edr-2025-full-book-6.06.2025-en.pdf.
- ↑ "Structure-Activity Relationships in the Cannabinoid series.". Marijuana Chemistry, Pharmacology, Metabolism, and Clinical Effects. New York: Academic Press. 1973. pp. 101–136.
- ↑ "Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol". Journal of Medicinal Chemistry 34 (11): 3310–3316. November 1991. doi:10.1021/jm00115a023. PMID 1659638.
- ↑ "Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630". British Journal of Pharmacology 126 (3): 665–672. February 1999. doi:10.1038/sj.bjp.0702351. PMID 10188977.
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