From HandWiki
Short description: Chemical compound
HHCV structure.png
Chemical and physical data
Molar mass288.431 g·mol−1
3D model (JSmol)

Hexahydrocannabivarin (HHCV, HHC-V) is a semi-synthetic cannabinoid derivative, the hydrogenated derivative of tetrahydrocannabivarin (THCV). It was first synthesised by Roger Adams in 1942 and produces only weak cannabinoid-like effects in animals.[1] More recently it has been sold as an ingredient in grey-market cannabinoid products. It has been investigated for potential antineoplastic activity in vitro.[2][3]

See also


  1. "Tetrahydrocannabinol homologs and analogs with marihuana activity. XIII.". Journal of the American Chemical Society 64 (3): 694–697. March 1942. doi:10.1021/ja01255a061. 
  2. "Antineoplastic Properties of THCV, HHC, HHCV and their anti-Proliferative effects on HPAF-II, MIA-paca2, Aspc-1, and PANC-1 PDAC Pancreatic Cell Lines.". Chemrxiv. 2022. doi:10.26434/chemrxiv-2022-v4zqc. 
  3. "Saturated Cannabinoids: Update on Synthesis Strategies and Biological Studies of These Emerging Cannabinoid Analogs". Molecules (Basel, Switzerland) 28 (17): 6434. September 2023. doi:10.3390/molecules28176434. PMID 37687263.