Chemistry:THCP-O-acetate
From HandWiki
THCP-O-acetate (THCP-O) is a semi-synthetic derivative of tetrahydrocannabiphorol (THCP) derived by acetylation of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gummy lollies, and is allegedly a potent and long-lasting psychoactive cannabinoid.[1]
Toxicity
In 2022, researchers at Portland State University who screened for the presence of reacted ketene as N-benzylacetamide reported that Vitamin E acetate, CBD-acetate, CBN-acetate and THC-O-acetate may break down to release ketene gas when heated at 340 °C (644 °F).[2][3]
Legality
Japan banned THCP-O-Acetate along with HHCP on December 26, 2023.[4]
See also
- Tetrahydrocannabiphorol
- Hexahydrocannabiphorol (HHCP)
- HHCP-O-acetate
- THC-O-acetate
- Dimethylheptylpyran (DMHP)
- HU-210
- THC-O-phosphate
- THC hemisuccinate
- THC morpholinylbutyrate
References
- ↑ "Waiting for CBD regulations in the US". Chemical & Engineering News 101 (28): 17–19. 2023. doi:10.1021/cen-10128-feature1. https://pubs.acs.org/doi/10.1021/cen-10128-feature1.
- ↑ "Vaping Cannabinoid Acetates Leads to Ketene Formation". Chemical Research in Toxicology 35 (7): 1202–1205. July 2022. doi:10.1021/acs.chemrestox.2c00170. PMID 35801872.
- ↑ "Proceedings of the 2022 Cannabis Clinical Outcomes Research Conference (CCORC) Orlando, FL, USA, May 19-20, 2022". Medical Cannabis and Cannabinoids 5 (1): 142–158. 2022. doi:10.1159/000527081.
- ↑ "Japan bans sale of 38 goods with synthetic cannabis compounds". The Japan Times. 22 December 2023. https://www.japantimes.co.jp/news/2023/12/22/japan/crime-legal/cannabis-like-substances-sales-banned/.
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