Chemistry:11-Hydroxycannabinol
From HandWiki
Short description: Chemical compound
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| Formula | C21H26O3 |
| Molar mass | 326.436 g·mol−1 |
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11-Hydroxycannabinol (11-OH-CBN) is the main active metabolite of cannabinol (CBN), one of the active components of cannabis,[1] and has also been isolated from cannabis itself.[2] It is more potent than CBN itself, acting as an agonist of CB1 with around the same potency as THC, but is a weak antagonist at CB2.[3][4]
See also
References
- ↑ "Metabolic formation and pharmacological effects of 11-hydroxycannabinol, an active metabolite of cannabinol.". Marihuana: an international research report.. National Campaign Against Drug Abuse, monograph series No. 7.. Canberra: Australian Government Printing Office. 1988. pp. 135–140.
- ↑ "Extraction and isolation of cannabinoids from marijuana seizures and characterization by 1H NMR allied to chemometric tools". Science & Justice 58 (5): 355–365. September 2018. doi:10.1016/j.scijus.2018.06.005. PMID 30193661.
- ↑ "The pharmacological activity of cannabinol and its major metabolite, 11-hydroxycannabinol". Chemical & Pharmaceutical Bulletin 35 (5): 2144–7. May 1987. doi:10.1248/cpb.35.2144. PMID 3664823.
- ↑ "Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase". Journal of Medicinal Chemistry 40 (20): 3228–33. September 1997. doi:10.1021/jm970126f. PMID 9379442.
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