Chemistry:JWH-116
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Short description: Chemical compound
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| Formula | C26H27NO |
| Molar mass | 369.508 g·mol−1 |
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JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB1 receptor is reported as Ki = 52 ± 5 nM.[1]
In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-116 are Schedule I Controlled Substances.[2]
See also
References
- ↑ "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor". Bioorganic & Medicinal Chemistry 11 (4): 539–49. February 2003. doi:10.1016/s0968-0896(02)00451-0. PMID 12538019.
- ↑ : Schedules of controlled substances
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