Chemistry:JWH-398
From HandWiki
Short description: Chemical compound
 | |
| Legal status | |
|---|---|
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| ChemSpider | |
| UNII | |
| Chemical and physical data | |
| Formula | C24H22ClNO |
| Molar mass | 375.90 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
  (what is this?) (verify) | |
JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It has mild selectivity for CB1 with a Ki of 2.3 nM and 2.8 nM at CB2.[2] This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate "herbal incense" products purchased from online shops between February and June 2009.[3] It was discovered by, and named after, John W. Huffman.[4]
In the United States, JWH-398 is a Schedule I controlled substance.[5]
See also
References
- ↑ Grozījumi Ministru kabineta 2005.gada 8.novembra noteikumos Nr.847 "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem"
- ↑ Cannabimimetic Indoles, Pyrroles, and Indenes: Structure–Activity Relationships and Receptor Interactions. The Cannabinoid Receptors. The Receptors.. Humana Press. 2009. doi:10.1007/978-1-59745-503-9. ISBN 978-1-58829-712-9.
- ↑ "Understanding the 'Spice' phenomenon". Lisbon: EMCDDA. November 2009. http://www.emcdda.europa.eu/attachements.cfm/att_80086_EN_Spice%20Thematic%20paper%20%E2%80%94%20final%20version.pdf.
- ↑ "Structure-Activity Relationships at the cb1 and cb2 Receptors for 1-Alkyl-3-(1-Naphthoyl-4 and 8-Halogen Substituted) Indoles". 19th Annual Symposium on the Cannabinoids. Burlington, Vermont: International Cannabinoid Research Society. 2009. p. 2.
- ↑ Controlled Substances listed by the DEA
 |  |
