Chemistry:Mepirapim
From HandWiki
Short description: Chemical compound
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| Formula | C19H27N3O |
| Molar mass | 313.445 g·mol−1 |
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MEPIRAPIM is an indole-based cannabinoid which differs from JWH-018 by having a 4-methylpiperazine group in place of the naphthyl group[1] and has been used as an active ingredient in synthetic cannabis products. It was first identified in Japan in 2013, alongside FUBIMINA.[2] MEPIRAPIM acts as a T-type calcium channelinhibitor and is only minimally active at the central CB1 receptor.[3]
Legality
Sweden's public health agency suggested to classify MEPIRAPIM as hazardous substance on November 10, 2014.[4]
See also
References
- ↑ "MEPIRAPIM". Cayman Chemical. https://www.caymanchem.com/app/template/Product.vm/catalog/15388.
- ↑ "Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products". Forensic Toxicology 32 (1): 105–115. January 2014. doi:10.1007/s11419-013-0217-2.
- ↑ "Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors". ACS Chemical Neuroscience 13 (9): 1395–1409. May 2022. doi:10.1021/acschemneuro.1c00822. PMID 35442021.
- ↑ "Cannabinoider föreslås bli klassade som hälsofarlig vara". http://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2014/november/cannabinoider-foreslas-bli-klassade-som-halsofarlig-vara/.
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