Chemistry:JTE-907
From HandWiki
Short description: Chemical compound
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| Formula | C24H26N2O6 |
| Molar mass | 438.472 g·mol−1 |
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JTE-907 is a drug used in scientific research that acts as a selective CB2 inverse agonist.[1][2] It has antiinflammatory effects in animal studies,[3] thought to be mediated by an interaction between the CB2 receptor and IgE.[4]
See also
References
- ↑ "In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor". The Journal of Pharmacology and Experimental Therapeutics 296 (2): 420–5. February 2001. PMID 11160626.
- ↑ "Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists". Journal of Medicinal Chemistry 49 (6): 2022–7. March 2006. doi:10.1021/jm050879z. PMID 16539390.
- ↑ "Involvement of cannabinoid CB(2) receptor-mediated response and efficacy of cannabinoid CB(2) receptor inverse agonist, JTE-907, in cutaneous inflammation in mice". European Journal of Pharmacology 520 (1–3): 164–71. September 2005. doi:10.1016/j.ejphar.2005.08.013. PMID 16153638.
- ↑ "Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice". Life Sciences 80 (5): 414–9. January 2007. doi:10.1016/j.lfs.2006.09.026. PMID 17055000.
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