Chemistry:Cannabitriol
From HandWiki
Short description: Group of isomers
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| Formula | C21H30O4 |
| Molar mass | 346.467 g·mol−1 |
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Cannabitriol ((+)-CBT, (S,S)-9,10-Dihydroxy-Δ6a(10a)-THC) is a phytocannabinoid first isolated in 1966,[1][2][3] an oxidation product of tetrahydrocannabinol which has been identified both as a trace component of cannabis and as a metabolite in cannabis users.[4] Its pharmacology has been little studied, though it has been found to act as an antiestrogen and aromatase inhibitor.[5][6]
See also
- 8,11-Dihydroxy-THC
- 9-OH-HHC
- Cannabicitran (also sometimes called CBT)
- Cannabiripsol
- Delta-3-THC
References
- ↑ Obata Y, Ishikawa Y. Studies on the Constituents of Hemp Plant (Cannabis sativa L.), Agricultural and Biological Chemistry 1966; 30(6): 619–620. doi:10.1080/00021369.1966.10858651
- ↑ "The structure of cannabitriol". Experientia 32 (3): 283–4. March 1976. doi:10.1007/BF01940792. PMID 1253891.
- ↑ "Isolation and characterization of (+)-cannabitriol and (-)-10-ethoxy-9-hydroxy-delta 6a[10a]-tetrahydrocannabinol: two new cannabinoids from Cannabis sativa L. extract". Lloydia 40 (3): 275–80. 1977. PMID 895385.
- ↑ "Instability and poor recovery of cannabinoids in urine, oral fluid, and hair". Forensic Science Review 30 (1): 33–49. January 2018. PMID 29273570.
- ↑ "Cannabinoid as Potential Aromatase Inhibitor through Molecular Modeling and Screening for Anti-Cancer Activity.". Dhaka University Journal of Pharmaceutical Sciences 19 (1): 47–58. June 2020. doi:10.3329/dujps.v19i1.47818.
- ↑ "Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer". Recent Patents on Anti-Cancer Drug Discovery 16 (2): 273–284. 2021. doi:10.2174/1574892816666210201115359. PMID 33563181.
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