Chemistry:Cycloheptyl CP 55,940

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Short description: Chemical compound

Cycloheptyl CP 55,940
Identifiers
CAS Number
Chemical and physical data
FormulaC25H42O3
Molar mass390.608 g·mol−1
3D model (JSmol)

Cycloheptyl CP 55,940 is a synthetic cannabinoid related to CP 55,940 but is a ring-expanded homologue with a cycloheptyl ring in place of the cyclohexyl ring. It was first synthesized by Pfizer in the 1980s.[1][2] It falls outside the definition of a "cyclohexylphenol derivative" since it does not have a cyclohexyl ring. Cycloheptyl CP 55,940 has similar potency to CP 55,940 itself, with an ED50 of 0.06 mg/kg in animal studies.[3]

See also

References

  1. "Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs". Molecular Pharmacology 44 (5): 1008–1015. November 1993. doi:10.1016/S0026-895X(25)13256-2. PMID 8246904. 
  2. "Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity". Drug Design and Discovery 13 (2): 155–166. November 1995. PMID 8872458. 
  3. Johnson MR, Melvin LS, "2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives.", US patent 4371720, issued 1 February 1983, assigned to Pfizer Inc.