Chemistry:THCP-O-acetate

Short description: Chemical compound

THCP-O-acetate

Identifiers
IUPAC name (6aR,10aR)-3-heptyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-yl acetate
Chemical and physical data
Formula	C25H36O3
Molar mass	384.560 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)Oc1cc(CCCCCCC)cc2OC(C)(C)[C@@H]3CCC(C)=C[C@H]3c21

THCP-O-acetate (THCP-O) is a semi-synthetic derivative of tetrahydrocannabiphorol (THCP) derived by acetylation of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gummy lollies, and is allegedly a potent and long-lasting psychoactive cannabinoid.

Toxicity

In 2022, researchers at Portland State University who screened for the presence of reacted ketene as N-benzylacetamide reported that Vitamin E acetate, CBD-acetate, CBN-acetate and THC-O-acetate may break down to release ketene gas when heated at 340 °C (644 °F).

The lowest concentration of inhaled ketene that produces a physiologically negative response is 5 ppm (5 parts per million). For this reason it is advised to exercise caution around THC-O acetate and other acetate esters of inhaled drugs.

Legality

Japan banned THCP-O-Acetate along with HHCP on December 26, 2023.

See also

• Tetrahydrocannabiphorol
• Hexahydrocannabiphorol (HHCP)
• HHCP-O-acetate
• THC-O-acetate
• Dimethylheptylpyran (DMHP)
• HU-210
• THC-O-phosphate
• THC hemisuccinate
• THC morpholinylbutyrate