Biology:Concentrative nucleoside transporter 2

Short description: Protein found in humans

Generic protein structure example

Concentrative nucleoside transporter 2 (CNT2) is a protein that in humans is encoded by the SLC28A2 gene.

See also

• Concentrative nucleoside transporters
• Nucleoside transporters
• Solute carrier family

Further reading

• "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• "Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.". Mol. Membr. Biol. 15 (4): 203–11. 1999. doi:10.3109/09687689709044322. PMID 10087507. 
• "Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.". J. Biol. Chem. 274 (35): 24475–84. 1999. doi:10.1074/jbc.274.35.24475. PMID 10455109. 
• "Differential expression of human nucleoside transporters in normal and tumor tissue.". Biochem. Biophys. Res. Commun. 280 (3): 951–9. 2001. doi:10.1006/bbrc.2000.4205. PMID 11162617. 
• "Differential kinetics of transport of 2',3'-dideoxyinosine and adenosine via concentrative Na+ nucleoside transporter CNT2 cloned from rat blood–brain barrier.". J. Pharmacol. Exp. Ther. 299 (2): 735–40. 2001. PMID 11602688. 
• "Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.". Am. J. Physiol. Renal Physiol. 283 (2): F344–9. 2002. doi:10.1152/ajprenal.00274.2001. PMID 12110519. 
• "Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia.". Blood 101 (6): 2328–34. 2003. doi:10.1182/blood-2002-07-2236. PMID 12411296. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.". Biochem. Biophys. Res. Commun. 307 (3): 696–703. 2003. doi:10.1016/S0006-291X(03)01259-2. PMID 12893280. 
• "Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.". Mol. Pharmacol. 65 (4): 925–33. 2004. doi:10.1124/mol.65.4.925. PMID 15044622. 
• "Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside.". Mol. Pharmacol. 67 (1): 273–9. 2005. doi:10.1124/mol.104.004408. PMID 15486050. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.". Pharmacogenet. Genomics 15 (2): 83–90. 2005. doi:10.1097/01213011-200502000-00004. PMID 15861032. 
• "Molecular determinants of specificity for synthetic nucleoside analogs in the concentrative nucleoside transporter, CNT2.". J. Biol. Chem. 281 (36): 26675–82. 2006. doi:10.1074/jbc.M513421200. PMID 16840788. 
• "Transcription factors involved in the expression of SLC28 genes in human liver parenchymal cells.". Biochem. Biophys. Res. Commun. 353 (2): 381–8. 2007. doi:10.1016/j.bbrc.2006.12.021. PMID 17187757. 
• "Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.". Mol. Membr. Biol. 24 (1): 53–64. 2007. doi:10.1080/09687860600942534. PMID 17453413. 
• "Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.". Biochemistry 46 (36): 10373–83. 2007. doi:10.1021/bi7009647. PMID 17696452. 
• "Identification and functional analysis of variants in the human concentrative nucleoside transporter 2, hCNT2 (SLC28A2) in Chinese, Malays and Indians.". Pharmacogenet. Genomics 17 (9): 783–6. 2007. doi:10.1097/FPC.0b013e3281c10e41. PMID 17700367.