Chemistry:10-Hydroxy-THC
From HandWiki
10-Hydroxy-THC (10α-OH-Δ8-THC) is a phytocannabinoid, identified in trace amounts as a component of Cannabis sativa in 2015. It has two epimers, 10α-THC and 10β-THC, of which the α epimer is the pharmacologically active component with similar or slightly higher potency compared to THC itself, while the β epimer is around 100x weaker in vitro and only partially substituted for THC in animal tests.[1] It can also be made synthetically, and has been sold as a designer drug.
See also
- 3'-Hydroxy-THC
- 8-Hydroxyhexahydrocannabinol
- 9-Hydroxyhexahydrocannabinol
- 8,11-Dihydroxytetrahydrocannabinol
- 10-Hydroxy-HHC
- 11-Hydroxy-THC
- 11-Hydroxy-Delta-8-THC
- Cannabiripsol
References
- ↑ "Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa". Journal of Natural Products 78 (6): 1271–1276. June 2015. doi:10.1021/acs.jnatprod.5b00065. PMID 26000707. Bibcode: 2015JNAtP..78.1271R.
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