Chemistry:HHC-acetate
From HandWiki
HHC-acetate (hexahydrocannabinol-O-acetate, HHC-O) is a semi-synthetic cannabinoid derivative which has been marketed since around 2022.[1][2]
Synthesis and chemistry
It is believed to be made in a three step process from cannabidiol extracted from industrial hemp by synthesis of Delta-8-THC from CBD, then hydrogenation of Delta-8-THC to Hexahydrocannabinol, then finally acetylation of HHC.[3]
Legality
The legal status of hexahydrocannabinol and derivatives such as HHC-O varies between countries leading to widespread sale in some jurisdictions in Europe and the US, but in France HHC and HHC-O were banned in 2023, and HHC is already banned in several other countries.[4] This molecule has also been banned in the Czech Republic.[5]
See also
References
- ↑ "Quantification of (9R)- and (9S)-hexahydrocannabinol (HHC) via GC-MS in serum/plasma samples from drivers suspected of cannabis consumption and immunological detection of HHC and related substances in serum, urine, and saliva". Drug Testing and Analysis 16 (5): 489–497. August 2023. doi:10.1002/dta.3570. PMID 37652872.
- ↑ Ujváry, István (2024). "Hexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review". Drug Testing and Analysis 16 (2): 127–161. doi:10.1002/dta.3519. PMID 37269160.
- ↑ "Hexahydrocannabinol (HHC) and related substances.". European Monitoring Centre for Drugs and Drug Addiction. 2023. https://www.emcdda.europa.eu/system/files/documents/2023-05/emcdda-technical-report-hhc-and-related-substances.pdf.
- ↑ "Actualité - L'ANSM classe l'hexahydrocannabinol (HHC) et deux de ses dérivés sur la liste des stupéfiants" (in fr). https://ansm.sante.fr/actualites/lansm-classe-lhexahydrocannabinol-hhc-et-deux-de-ses-derives-sur-la-liste-des-stupefiants.
- ↑ Fodor, Anna (2024-02-26). "EC confirms Czech government's decision to ban HHC". Radio Prague International. https://english.radio.cz/ec-confirms-czech-governments-decision-ban-hhc-8809645.
 |  |
