Chemistry:LY-334370

Short description: Chemical compound

LY-334370

Names
Preferred IUPAC name 4-Fluoro-N-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]benzamide
Other names LY-334,370
Identifiers
CAS Number	182563-08-2 Y
3D model (JSmol)	Interactive image
ChemSpider	4470773 N
IUPHAR/BPS	20 151
MeSH	C108218
PubChem CID	5311258
UNII	5Q7I1WL2UY Y
InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26) N Key: MDMJLMDBRQXOOI-UHFFFAOYSA-N N InChI=1/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26) Key: MDMJLMDBRQXOOI-UHFFFAOYAA
SMILES CN1CCC(c2c3cc(N([H])C(c4ccc(F)cc4)=O)ccc3n([H])c2)CC1
Properties
Chemical formula	C21H22FN3O
Molar mass	351.425 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

LY-334370 is a selective 5-HT_1F receptor agonist which was under development by Eli Lilly and Company for the treatment of migraine headaches. The drug showed efficacy in a phase II clinical trial but further development was halted due to toxicity detected in animals.

See also

• CP-135807
• Lasmiditan
• SN-22

External links

• 4-fluoro-N-(3-(1-methyl-4-piperidinyl)-1H-indol-5-yl)benzamide at the US National Library of Medicine Medical Subject Headings (MeSH)