Chemistry:PTI-1
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Short description: Chemical compound
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| Formula | C21H29N3S |
| Molar mass | 355.54 g·mol−1 |
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PTI-1 (SGT-48) is an indole-based synthetic cannabinoid.[1] It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-2. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.[2][3][4]
See also
References
- ↑ "PTI-1". Cayman Chemical. https://www.caymanchem.com/app/template/Product.vm/catalog/9001948.
- ↑ Adam-Worrall J, Morrison AJ, Wishart G, Kiyoi T, McArthur DR, "(Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor.", US patent 7700634, issued 20 April 2010, assigned to Organon NV
- ↑ Paul David Ratcliffe PD, Adam-Worrall J, Morrison AJ, Francis SJ, Kiyoi T, "Indole Derivatives", US patent 7763732, issued 27 July 2010, assigned to Organon NV
- ↑ "Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists". Bioorganic & Medicinal Chemistry Letters 21 (6): 1748–53. March 2011. doi:10.1016/j.bmcl.2011.01.082. PMID 21316962.
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