Chemistry:ZC-B

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Short description: Chemical compound
ZC-B
WO2021-0137908-1 structure.png
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC11H14BrNO2
Molar mass272.142 g·mol−1
3D model (JSmol)

ZC-B (3-(4-bromo-2,5-dimethoxyphenyl)azetidine) is a phenethylamine derivative which acts as a serotonin receptor agonist selective for the 5-HT2 subtypes, with an EC50 of 1.6nM at 5-HT2A, vs 5.8nM at 5-HT2C. It is related to psychedelic phenethylamine derivatives such as 2C-B and mescaline but with the ethylamine side chain replaced by an azetidine ring.[1]

See also

References

  1. Kristensen JL, Jensen AA, Märcher-Rørsted E, "5-HT2A Agonists for Use in Treatment of Depression.", US patent 2021/0137908, published 13 May 2021, assigned to Lophora ApS.