Chemistry:Fedotozine
From HandWiki
Short description: Chemical compound
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Routes of administration | Oral |
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Formula | C22H31NO4 |
Molar mass | 373.493 g·mol−1 |
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Fedotozine (INN; JO 1196 for the (-) tartrate salt) is an opioid drug which acts as a peripherally specific selective κ1-opioid receptor agonist with preference for the κ1A subtype.[1] It was under investigation for the treatment of gastrointestinal conditions like irritable bowel syndrome and functional dyspepsia and made it to phase III clinical trials,[1][2][3] but ultimately development was discontinued and it was never marketed.
See also
References
- ↑ 1.0 1.1 "Pharmacology and clinical experience with fedotozine". Expert Opinion on Investigational Drugs 10 (1): 97–110. January 2001. doi:10.1517/13543784.10.1.97. PMID 11116283.
- ↑ "Novel developments with selective, non-peptidic kappa-opioid receptor agonists". Expert Opinion on Investigational Drugs 6 (10): 1351–68. October 1997. doi:10.1517/13543784.6.10.1351. PMID 15989506.
- ↑ "Peripheral opioids for functional GI disease: a reappraisal". Digestive Diseases 24 (1–2): 91–8. 2006. doi:10.1159/000090312. PMID 16699267.
![]() | Original source: https://en.wikipedia.org/wiki/Fedotozine.
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