Chemistry:Nexeridine
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Revision as of 22:59, 17 July 2022 by imported>JTerm (fixing)
Short description: Chemical compound
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| Formula | C19H29NO2 |
| Molar mass | 303.446 g·mol−1 |
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Nexeridine[1] (INN), or as nexeridine hydrochloride (USAN) (code name Compound 673-082), is an opioid analgesic with a similar structure to those of pethidine and tramadol.[2][3][4] It was synthesized and assayed in 1975 but was never marketed.[2] The active isomer is (1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl]-2-phenylcyclohexyl acetate hydrochloride (1:1).[5]
References
- ↑ "1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters" US patent 3974157
- ↑ Jump up to: 2.0 2.1 Dictionary of Pharmacological Agents. CRC Press. 21 November 1996. pp. 1417–. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC&pg=PA1417.
- ↑ Medicinal Chemistry. New Age International. 1 January 2005. pp. 268–269. ISBN 978-81-224-1565-0. https://books.google.com/books?id=07g30rxCA0EC&pg=PA268.
- ↑ Unlisted Drugs, Volumes 27-28. Pharmaceutical Section, Special Libraries Association.. 1975. https://books.google.com/books?id=9xZtAAAAMAAJ.
- ↑ "(1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl-2-phenylcyclohexyl acetate hydrochloride (1:1)"]. ChemSpider. http://www.chemspider.com/Chemical-Structure.34995858.html.
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