Chemistry:5F-CUMYL-PEGACLONE

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Short description: Chemical compound
5F-CUMYL-PEGACLONE
5F-CUMYL-PEGACLONE Structure.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC25H27FN2O
Molar mass390.502 g·mol−1
3D model (JSmol)

5F-CUMYL-PEGACLONE (5F-SGT-151, SGT-269) is a gamma-carboline based synthetic cannabinoid that has been sold as a designer drug, first being identified in Germany in 2017. It acts as a potent full agonist of the CB1 receptor. [1][2] It appears to be more toxic than related compounds such as CUMYL-PEGACLONE, and has been linked to numerous serious adverse reactions, some fatal.[3]

See also

References

  1. "Human phase I metabolism of the novel synthetic cannabinoid 5F-CUMYL-PEGACLONE". Forensic Toxicology 37 (1): 154–163. 2019. doi:10.1007/s11419-018-0447-4. PMID 30636984. 
  2. "In vitro activity profiling of Cumyl-PEGACLONE variants at the CB1 receptor: Fluorination versus isomer exploration". Drug Testing and Analysis 12 (9): 1336–1343. June 2020. doi:10.1002/dta.2870. PMID 32490586. https://biblio.ugent.be/publication/8687072. 
  3. "Four cases of death involving the novel synthetic cannabinoid 5F-Cumyl-PEGACLONE.". Forensic Toxicology 38 (2): 314–326. 2019. doi:10.1007/s11419-019-00514-w.