Chemistry:Cannabidiorcol
From HandWiki
Short description: Phytocannabinoid
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| Formula | C17H22O2 |
| Molar mass | 258.361 g·mol−1 |
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Cannabidiorcol (CBDO, CBD-C1, O-1821) is a phytocannabinoid found naturally in Cannabis in trace concentrations. It is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors and is mainly active as an agonist of the TRPV2 cation channel, through which it produces antiinflammatory effects,[1] but can also promote tumorigenesis at high concentrations.[2]
See also
References
- ↑ "Combination therapy of a TRPV2 agonist with a TNF inhibitor achieves sustained suppression of disease severity and reduced joint damage". Clinical and Experimental Immunology 211 (3): 233–238. March 2023. doi:10.1093/cei/uxac124. PMID 36571199.
- ↑ "Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma". British Journal of Cancer 127 (8): 1424–1439. November 2022. doi:10.1038/s41416-022-01896-2. PMID 35896815.
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