Biology:TRPM4
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Short description: Protein-coding gene in the species Homo sapiens
![]() Generic protein structure example |
Transient receptor potential cation channel subfamily M member 4 (hTRPM4), also known as melastatin-4, is a protein that in humans is encoded by the TRPM4 gene.[1][2]
TRPM4 Channel Blocker
See also
References
- ↑ "Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform". Proc. Natl. Acad. Sci. U.S.A. 98 (19): 10692–7. September 2001. doi:10.1073/pnas.191360198. PMID 11535825.
- ↑ "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. December 2005. doi:10.1124/pr.57.4.6. PMID 16382100.
Further reading
- Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. 704. Berlin: Springer. pp. 700. ISBN 978-94-007-0264-6.
- "TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization". Cell 109 (3): 397–407. 2002. doi:10.1016/S0092-8674(02)00719-5. PMID 12015988.
- "TRPM4 regulates calcium oscillations after T cell activation". Science 306 (5700): 1374–1377. 2004. doi:10.1126/science.1098845. PMID 15550671.
- "Insights into TRPM4 function, regulation and physiological role". Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology. 179. 2007. pp. 269–85. doi:10.1007/978-3-540-34891-7_16. ISBN 978-3-540-34889-4.
- "Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4". Nat Immunol 8 (3): 312–320. 2007. doi:10.1038/ni1441. PMID 17293867. https://lirias.kuleuven.be/bitstream/123456789/44883/2/Nature+Immunology+Mast+Cell.pdf.
- "The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells". Nat Immunol 9 (10): 1148–56. 2008. doi:10.1038/ni.1648. PMID 18758465.
External links
- TRPM4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
![]() | Original source: https://en.wikipedia.org/wiki/TRPM4.
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