Chemistry:Etazocine
From HandWiki
Short description: Chemical compound
 | |
 | |
| Clinical data | |
|---|---|
| Other names | NIH-7856 ((±)-form); GPA-208 ((−)-form); GPA-2087 ((−)-form); NIH-8178 ((−)-form); FDA-0487 ((−)-form) |
| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| Chemical and physical data | |
| Formula | C17H25NO |
| Molar mass | 259.393 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Etazocine (NIH-7856) is an opioid analgesic of the benzomorphan family which was never marketed.[1][2] It acts as a partial agonist of the opioid receptors, with mixed agonist and antagonist effects.[1] In animal studies, it was shown to induce analgesia, dependency, and respiratory depression, with overall effects similar to those of morphine, but with substantially reduced potency in comparison.[1][2][3]
See also
- Benzomorphan
References
- ↑ 1.0 1.1 1.2 Bulletin, problems of drug dependence. National Academies. 1969. pp. 5820–5821. NAP:10503. https://books.google.com/books?id=BUcrAAAAYAAJ&pg=PA5820. Retrieved 22 April 2012.
- ↑ 2.0 2.1 "The respiratory effects of a potent analgesic (GPA 2087) in man". British Journal of Anaesthesia 43 (12): 1129–35. December 1971. doi:10.1093/bja/43.12.1129. PMID 5156297.
- ↑ National Research Council (U.S.). Committee on Problems of Drug Dependence (1970). Report of the annual scientific meeting. National Research Council. https://books.google.com/books?id=uN9rAAAAMAAJ. Retrieved 22 April 2012.
 |  |
