Chemistry:Norpipanone

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Short description: Opioid analgesic drug
Norpipanone
Norpipanone2DCSD.svg
Clinical data
Other namesHerchst 10495, NIH-7557
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC23H29NO
Molar mass335.491 g·mol−1
3D model (JSmol)

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina , and other countries.[1][2] It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance.[1][2] In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2014). The salts in use are the hydrobromide (free base conversion ratio 0.806) and hydrochloride (0.902).

Synthesis

Norpipanone synthesis:[3][4]

See also

References

  1. 1.0 1.1 Buckingham, John B (December 1995). Dictionary of Organic Compounds. CRC Press. p. 2883. ISBN 978-0-412-54090-5. https://books.google.com/books?id=C3Uo1co4Wv0C&pg=PA2883. Retrieved 11 May 2012. 
  2. 2.0 2.1 Patterson, David S. (12 March 2002). Foreign Relations of the United States, 1961-1963, Volume XXV: Organization of Foreign Policy; Information Policy; United Nations; Scientific Matters. Government Printing Office. pp. 766–767. ISBN 978-0-16-050885-1. https://books.google.com/books?id=wn4hSwZRaXsC&pg=PA766. Retrieved 11 May 2012. 
  3. "113. Analgesics. Part I. Esters and ketones derived from α-amino-ω-cyano-ωωdiarylalkanes". Journal of the Chemical Society (Resumed) (Chemical Society): 500–510. 1949. doi:10.1039/JR9490000500. 
  4. "Über eine neue Klasse von spasmolytisch und analgetisch wirkenden Verbindungen, I". Justus Liebigs Annalen der Chemie 561: 52–86. 1949. doi:10.1002/jlac.19495610107.