Chemistry:N-t-BOC-MDMA
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| Formula | C16H23NO4 |
| Molar mass | 293.363 g·mol−1 |
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N-t-BOC-MDMA is a chemical compound which can be both a synthetic precursor to, or a prodrug of the empathogenic drug MDMA. It was first identified in Australia in 2015 as a seizure by customs, and has subsequently been found in China, the Netherlands and other European countries. Originally it was thought to be intended as a non-illegal form of MDMA which could be easily converted into the prohibited final product after importation, however one seizure by police found N-t-BOC-MDMA in the process of being pressed into pills, and experiments with simulated gastric fluid confirmed that it can be broken down to MDMA by human stomach acid. Similar N-protected compounds such as N-t-BOC-methamphetamine, N-p-tosyl-methamphetamine, N-t-BOC-ketamine, N-t-BOC-norketamine, and N-methoxycarbonyl-MDA have also been encountered by law enforcement.[1][2][3][4][5][6][7]
Legal status
N-t-BOC-MDMA has been specifically listed as an illicit drug in Singapore and South Korea,[8][9] but is also controlled by general drug analogue provisions in Australia and various other countries.
See also
- 1-Boc-4-AP - a masked fentanyl precursor
- Gabapentin enacarbil
- O-Acetylpsilocin
- Lys-MDA
References
- ↑ "Identification and characterization of N-tert-butoxycarbonyl-MDMA: a new MDMA precursor". Drug Testing and Analysis 9 (3): 399–404. March 2017. doi:10.1002/dta.2059. PMID 27574107.
- ↑ "Rapid detection of tert-butoxycarbonyl-methamphetamine by direct analysis in real time time-of-flight mass spectrometry". Forensic Toxicology 36 (2): 261–269. 2018. doi:10.1007/s11419-017-0400-y. PMID 29963202.
- ↑ "Illicit drug chemical profiling: current and future state.". Australian Journal of Forensic Sciences 50 (6): 689–696. 2018. doi:10.1080/00450618.2018.1424244.
- ↑ "Another chemically masked drug: p‐tosyl methylamphetamine.". Drug Testing and Analysis 10 (5): 898–905. 2018. doi:10.1002/dta.2363. PMID 29388381.
- ↑ "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences 51: S217–S219. 2019. doi:10.1080/00450618.2019.1569135.
- ↑ European Monitoring Centre for Drugs and Drug Addiction (2019). "Drug precursor developments in the European Union". EMCDDA Papers. Luxembourg: Publications Office of the European Union. https://www.emcdda.europa.eu/system/files/publications/12137/20195889_TDAU19003ENN_1.pdf.
- ↑ "Prosecutors Detail 500 Kilogram Ketamine Precursor Raid.". ICRT.com.. 3 March 2020. https://www.icrt.com.tw/info_details.php?mlevel1=6&mlevel2=12&news_id=174698.
- ↑ "Singapore Misuse of Drugs (Amendment No. 2) Regulations 2020". https://sso.agc.gov.sg/SL-Supp/S750-2020/Published/20200903?DocDate=20200903.
- ↑ "Han-soo L. Ministry lists 10 substances on temporary narcotics list.". Korea Biomedical Review. 11 May 2018. https://www.koreabiomed.com/news/articleView.html?idxno=3244.
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