Chemistry:Lys-MDA

From HandWiki
Short description: Chemical compound
Lys-MDA
Lys-MDA structure.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
Chemical and physical data
FormulaC16H25N3O3
Molar mass307.394 g·mol−1
3D model (JSmol)

Lys-MDA (Lysine-MDA, N-(L-lysinamidyl)-3,4-methylenedioxyamphetamine) is a substituted amphetamine derivative with empathogenic effects, which acts as a prodrug for MDA with a slower onset of effects and longer duration of action. Lys-MDA, along with the related derivative Lys-MDMA, are in early stage human clinical trials as potential treatments for treatment-resistant depression and post-traumatic stress disorder.Currently new MDMA prodrugs are in the development phase at MiHKAL GmbH in Switzerland.[1][2][3][4]

Lys-MDMA [1]

See also

References

  1. "MindMed announces Phase 1 study of MDMA-like substances.". Drug Discovery and Development. 21 September 2022. https://www.drugdiscoverytrends.com/mindmed-announces-phase-1-study-of-mdma-like-substances/. 
  2. "MindMed Collaborators Dose First Patient in Phase 1 Investigator-Initiated Trial of MDMA-Like Substances.". Biospace.com. 20 September 2022. https://www.biospace.com/article/releases/mindmed-collaborators-dose-first-patient-in-phase-1-investigator-initiated-trial-of-mdma-like-substances/. 
  3. Grill M, "Novel Safrylamine derivatives having prodrug properties.", WO patent 2022/053696, published 17 March 2022, assigned to Compass Pathfinder Limited.
  4. Clark S, Duncton MA, "Methylenedioxymethamphetamine and Related Psychedelics and Uses Thereof", WO patent 2023/283373, published 12 January 2023, assigned to Terran Biosciences Inc.