Chemistry:NBoc-DMT

From HandWiki

NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family.[1][2] It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group.[1][2]

NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping).[1] It may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally.[3][4] NB-DMT has been claimed to have about 25% of the potency of DMT by weight.[1] It was first detected as a designer drug being sold online by February 2024.[1]

NB-DMT is a Schedule I controlled substance in Russia.[1] The drug is not an explicitly controlled substance in the United States[5] or in Canada.[6] A number of other NBoc designer drugs have also been encountered.[1][7]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 "DMT BOC (NB-DMT)" (in ru). https://aipsin.com/newsubstance/1361/. 
  2. ↑ 2.0 2.1 "Tert-butyl 3-[2-(dimethylamino)ethylindole-1-carboxylate"]. PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/141803940. 
  3. ↑ Alexander M, Duncton J, Clark S, "N,N-dimethyltryptamine and related psychedelics and uses thereof.", US patent 2024/0116870, published 11 April 2024
  4. ↑ Buchner M, "Novel N,N-Dimethyltryptamine (DMT) derivatives and uses thereof.", WO patent 2024/121253, published 13 June 2024
  5. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026, https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf 
  6. ↑ "Controlled Drugs and Substances Act". 5 December 2025. https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 
  7. ↑ "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences 51: S217–S219. 2019. doi:10.1080/00450618.2019.1569135. 




Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:NBoc-DMT&oldid=4243368"