Chemistry:Triphenyliodoethylene

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Short description: Chemical compound
Triphenyliodoethylene
Triphenyliodoethylene.png
Clinical data
Other namesTPIE; Iodotriphenylethylene; Phenylstilbene iodide; Triphenylvinyl iodide
Drug classNonsteroidal estrogen
Identifiers
PubChem CID
Chemical and physical data
FormulaC20H15I
Molar mass382.244 g·mol−1
3D model (JSmol)

Triphenyliodoethylene (TPIE), also known as iodotriphenylethylene or as phenylstilbene iodide, as well as triphenylvinyl iodide, is a synthetic nonsteroidal estrogen of the triphenylethylene group that is related to triphenylchloroethylene and triphenylbromoethylene and was never marketed.[1][2][3]

See also

References

  1. "Synthetic oestrogens related to triphenylethylene". Proceedings of the XIth International Congress of Pure and Applied Chemistry: Chemistry in relation to medicine and theropeutics [sic], chemistry in relation to fuel, power and transport. Hepworth. 1947. p. 149. https://books.google.com/books?id=bMMfAQAAMAAJ. "In fact the cestrogenic activity of either triphenylbromoethylene or triphenyliodoethylene (J. 3d. Robson, A. Schonberg and H. A. Fahim)(3) (Table 1) compares with that of triphenylchloroethylene. A True Oestrogen and A Pro-oestrogen." 
  2. British Abstracts. Bureau of Abstracts. 1952. p. 549. https://books.google.com/books?id=D0E_AAAAYAAJ. "Roughly quantitative data are reported for the antagonism between oestrogens (oestradiol, stilboestrol, doisynolic acid, allenolic acid, and triphenyliodoethylene) and progesterone, methyltestosterone, and testosterone propionate given [...]" 
  3. Egyptian Veterinary Medical Association (1966). Annual Veterinary Congress, Proceedings. L'Institut Francais d'Archéologie Orientale. p. 392. https://books.google.com/books?id=vztXAAAAYAAJ. "But the synthetic oestrogens tested e.g. stilboesterol, triphenyliodoethylene, diosynolic acid and allenolic acid produce constant inhibition of the uterine motility."