Chemistry:Dianol
From HandWiki
Short description: Chemical compound
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| Formula | C18H20O2 |
| Molar mass | 268.356 g·mol−1 |
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Dianol is a synthetic, nonsteroidal estrogen that was never marketed.[1] It is a dimer and impurity of anol, and was, along with hexestrol, involved in erroneous findings of highly potent estrogenic activity with anol.[2][3][4] Although a potent estrogen, it requires a dose of 100 μg to show activity, whereas hexestrol shows activity with a mere dose of 0.2 μg.[5]
See also
References
- ↑ "Synthetic œstrogens in treatment". The Irish Journal of Medical Science 25 (7): 305–314. 2008. doi:10.1007/BF02950685. ISSN 0021-1265.
- ↑ "Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens". Tamoxifen: Pioneering Medicine in Breast Cancer. Milestones in Drug Therapy. Springer Science & Business Media. 23 July 2013. pp. 3–. doi:10.1007/978-3-0348-0664-0_1. ISBN 978-3-0348-0664-0. https://books.google.com/books?id=p-W5BAAAQBAJ&pg=PA3.
- ↑ "Possibilities in the Realm of Synthetic Estrogens". Vitamins and Hormones. 3. Academic Press. 1 January 1945. pp. 232–. doi:10.1016/S0083-6729(08)61113-9. ISBN 978-0-08-086600-0. https://archive.org/details/in.ernet.dli.2015.5563.
- ↑ "Nature as a Source of Drugs: Drugs from Natural Products". The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs. John Wiley & Sons. 11 January 2011. pp. 177–. ISBN 978-3-527-32669-3. https://books.google.com/books?id=iDNy0XxGqT8C&pg=PA177.
- ↑ "Synthetic estrogens and the relation between their structure and their activity". Chemical Reviews 37 (3): 481–598. December 1945. doi:10.1021/cr60118a004. PMID 21013428.
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