Chemistry:Orestrate

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Short description: Chemical compound
Orestrate
Orestrate.svg
Clinical data
Other namesEstradiol 3-propionate 17β-(1-cyclohexenyl) ether; 17β-(Cyclohexen-1-yloxy)-estra-1,3,5(10)-trien-3-ol propionate
Drug classEstrogen; Estrogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC27H36O3
Molar mass408.582 g·mol−1
3D model (JSmol)

Orestrate (INN), also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is an estrogen medication and estrogen ester which was never marketed.[1][2][3][4][5] It is the C3 propionate ester and C17β-(1-cyclohexenyl) ether of estradiol.[1][5]

See also

References

  1. 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 898, 905. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA905. 
  2. "1,3,5(10)-Estratrien-17 -yl enol ethers and acetals. New classes of orally and parenterally active estrogenic derivatives". Journal of Medicinal Chemistry 16 (2): 123–127. February 1973. doi:10.1021/jm00260a009. PMID 4683106. 
  3. "Effect of two orally active estradiol derivatives on sulfobromphthalein retention in rats". Pharmacological Research Communications 6 (2): 135–145. April 1974. doi:10.1016/s0031-6989(74)80021-4. PMID 4438394. 
  4. "Orestratum". Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. 12 March 2013. pp. 331–. ISBN 978-3-642-65035-2. https://books.google.com/books?id=4TWnBgAAQBAJ&pg=PA331. 
  5. 5.0 5.1 Design of biopharmaceutical properties through prodrugs and analogs: a symposium. The Academy. 1977. p. 7. ISBN 978-0-917330-16-2. https://books.google.com/books?id=T7zwAAAAMAAJ.