Chemistry:ZK-283197

From HandWiki
Short description: Chemical compound
ZK-283197
Clinical data
Other namesBAY 86-5310; SH-T04211C
Routes of
administration
By mouth[1]
Drug classEstrogen; Selective ERβ agonist
Identifiers
CAS Number

ZK-283197 (also known as BAY 86-5310 or SH-T04211C) is a selective and orally active ERβ agonist which was under development by Bayer Healthcare AG for the treatment of vasomotor symptoms.[1][2] It reached phase II clinical trials prior to the discontinuation of its development.[1] Its development was terminated in 2014.[1]

References

  1. 1.0 1.1 1.2 1.3 "ZK 283197". AdisInsight. Springer Nature Switzerland AG. https://adisinsight.springer.com/drugs/800039952. 
  2. Pietras RJ, Jung ME, "Methods of using estrogen receptor-beta ligands as radiation mitigators", US patent 332204, published 2015-01-15