Chemistry:Phenestrol
From HandWiki
Short description: Chemical compound
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| Other names | Fenestrol; NSC-183736; hexestrol bis[4-[bis(2-chloroethyl)amino]phenylacetate |
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| Formula | C42H48Cl4N2O4 |
| Molar mass | 786.66 g·mol−1 |
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Phenestrol, or fenestrol, also known as hexestrol bis[4-[bis(2-chloroethyl)amino]phenylacetate, is a synthetic, nonsteroidal estrogen and cytostatic antineoplastic agent (i.e., chemotherapy drug) and a chlorphenacyl nitrogen mustard ester of hexestrol which was developed in the early 1960s for the treatment of hormone-dependent tumors but was never marketed.[1][2][3][4]
See also
References
- ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 163–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA163.
- ↑ National Cancer Institute (U.S.); Onkologicheskiĭ nauchnyĭ t͡sentr (Akademii͡a medit͡sinskikh nauk SSSR) (1981). Experimental evaluation of antitumor drugs in the USA and USSR and clinical correlations. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute. p. 17. https://books.google.com/books?id=auZ3FSFQiT4C.
- ↑ "[Properties of alkylating derivatives of estrogens]" (in ru). Eksperimental'naia Onkologiia 6 (2): 50–54. 1984. PMID 6510335.
- ↑ "[The antineoplastic activity of testiphenon]" (in ru). Voprosy Onkologii 34 (11): 1363–1368. 1988. PMID 3201773.
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