Chemistry:Cloxestradiol acetate

Short description: Chemical compound

Cloxestradiol acetate

Clinical data
Trade names	Genovul
Other names	17-(2,2,2-Trichloroethoxy)estradiol O,O-diacetate; 1-{[(17β)-3-Acetoxyestra-1,3,5(10)-trien-17-yl]oxy}-2,2,2-trichloroethyl acetate
Pregnancy category	X (Contraindicated)
Drug class	Estrogen; Estrogen ester; Estrogen ether
Identifiers
IUPAC name [(8R,9S,13S,14S,17S)-17-(1-Acetyloxy-2,2,2-trichloroethoxy)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate
CAS Number	15686-44-9
PubChem CID	71586995
ChemSpider	34989697
UNII	CWU34U962K
Chemical and physical data
Formula	C24H29Cl3O5
Molar mass	503.84 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)OC1=CC2=C(C=C1)C3CCC4(C(C3CC2)CCC4OC(C(Cl)(Cl)Cl)OC(=O)C)C
InChI InChI=1S/C24H29Cl3O5/c1-13(28)30-16-5-7-17-15(12-16)4-6-19-18(17)10-11-23(3)20(19)8-9-21(23)32-22(24(25,26)27)31-14(2)29/h5,7,12,18-22H,4,6,8-11H2,1-3H3/t18-,19-,20+,21+,22?,23+/m1/s1 Key:UEVLJPRROXDIPO-CUFSGNDSSA-N

Cloxestradiol acetate (brand name Genovul), also known as 17-(2,2,2-trichloroethoxy)estradiol O,O-diacetate, is a synthetic steroidal estrogen derived from estradiol. It is the O,O-diacetate ester of cloxestradiol, which, in contrast to cloxestradiol acetate, was never marketed.

See also

• List of estrogen esters § Estradiol esters
• Cloxotestosterone acetate