Chemistry:Hexolame

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Short description: Chemical compound
Hexolame
Hexolame.svg
Clinical data
Other names17β-((6-Hydroxyhexyl)amino)estradiol; 17β-[(6-Hydroxyhexyl)amino]estra-1,3,5(10)-trien-3-ol; N-(3-Hydroxy-1,3,5(10)-estratrien 17-yl)-6-hydroxyhexylamine
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC24H37NO2
Molar mass371.565 g·mol−1
3D model (JSmol)

Hexolame, also known as 17β-((6-hydroxyhexyl)amino)estradiol, is a synthetic, steroidal estrogen and a 17β-aminoestrogen with anticoagulant effects that was first described in 1990 and was never marketed.[1][2][3]

References

  1. Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. 2001. p. 12610. ISBN 978-3-527-30247-5. https://books.google.com/books?id=1nBqAAAAMAAJ. 
  2. "The anticoagulant effect of hexolame, N-(3-hydroxy-1,3,5(10)-estratrien-17 beta-yl)-6-hydroxyhexylamine, another amino-estrogen with prolonged anticoagulant effect". Steroids 55 (2): 83–86. February 1990. doi:10.1016/0039-128x(90)90030-f. PMID 2326832. 
  3. "Comparison of the time course of anticoagulant and estrogenic effects of prolame, butolame, pentolame and hexolame, a homologous series of 17 beta-amino estrogens". Proceedings of the Western Pharmacology Society 36: 143–147. 1993. PMID 8378368.