Chemistry:Panomifene
From HandWiki
Short description: Chemical compound
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| Other names | GYKI-13504; EGIS-5650 |
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| Formula | C25H24F3NO2 |
| Molar mass | 427.467 g·mol−1 |
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Panomifene (INN; developmental codes GYKI 13504 and EGIS 5650) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group related to tamoxifen that was under development as an antineoplastic agent by Egis Pharmaceuticals and IVAX Drug Research Institute in the 1990s for the treatment of breast cancer, but it was never marketed.[1][2][3][4][5][6] It reached phase II clinical trials before development was terminated.[2] The drug was described in 1981.[1]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 930–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA930.
- ↑ 2.0 2.1 "Panomifene". AdisInsight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800002425.
- ↑ "Antiestrogens and Partial Agonists". Estrogens and Antiestrogens I: Physiology and Mechanisms of Action of Estrogens and Antiestrogens. Springer Science & Business Media. 6 December 2012. pp. 60–. ISBN 978-3-642-58616-3. https://books.google.com/books?id=0BfrCAAAQBAJ&pg=PA60.
- ↑ "Pharmacological Different Administration Routes - Oral vs Transdermal". Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogen. Springer Science & Business Media. 6 December 2012. pp. 292–. ISBN 978-3-642-60107-1. https://books.google.com/books?id=wBvyCAAAQBAJ&pg=PA292.
- ↑ "Visible-Light-Induced Redox Reactions by Ruthenium Photoredox Catalyst". Ruthenium in Catalysis. Springer. 18 October 2014. pp. 385–. ISBN 978-3-319-08482-4. https://books.google.com/books?id=sjndBAAAQBAJ&pg=PA385.
- ↑ "Antiestrogens, antiandrogens". Acta Physiologica Hungarica 84 (4): 405–406. 1996. PMID 9328614.
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