Chemistry:Acolbifene

Short description: Chemical compound

Acolbifene

Clinical data
Other names	EM-652; SCH-57068
Drug class	Selective estrogen receptor modulator
Identifiers
IUPAC name (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-2H-chromen-7-ol
CAS Number	252555-01-4
PubChem CID	155435
ChemSpider	136930
UNII	KXC7811DBY
ChEMBL	ChEMBL68055
Chemical and physical data
Formula	C29H31NO4
Molar mass	457.570 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C([C@@H](OC2=C1C=CC(=C2)O)C3=CC=C(C=C3)OCCN4CCCCC4)C5=CC=C(C=C5)O
InChI InChI=1S/C29H31NO4/c1-20-26-14-11-24(32)19-27(26)34-29(28(20)21-5-9-23(31)10-6-21)22-7-12-25(13-8-22)33-18-17-30-15-3-2-4-16-30/h5-14,19,29,31-32H,2-4,15-18H2,1H3/t29-/m0/s1 Key:DUYNJNWVGIWJRI-LJAQVGFWSA-N

Acolbifene (INN) (developmental code names EM-652, SCH-57068) is a nonsteroidal selective estrogen receptor modulator (SERM) which, as of 2015, is in phase III clinical trials for the treatment of breast cancer.

See also

• Acolbifene/prasterone
• List of investigational sex-hormonal agents § Estrogenics

External links

• Acolbifene - AdisInsight