Chemistry:Pentolame
From HandWiki
Short description: Chemical compound
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| Other names | 17β-((5-Hydroxypentyl)amino)estradiol; 17β-[(5-Hydroxypentyl)amino]estra-1,3,5(10)-trien-3-ol |
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| Formula | C23H35NO2 |
| Molar mass | 357.538 g·mol−1 |
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Pentolame, also known as 17β-((5-hydroxypentyl)amino)estradiol is a synthetic, steroidal estrogen and a 17β-aminoestrogen with anticoagulant effects that was first described in 1993 and was never marketed.[1][2][3]
References
- ↑ "Anticoagulant and estrogenic effects of two new 17 beta-aminoestrogens, butolame [17 beta-(4-hydroxy-1-butylamino)-1,3,5(10)-estratrien-3-ol] and pentolame [17 beta-(5-hydroxy-1-pentylamino)-1,3,5(10)-estratrien-3-ol]". Steroids 58 (10): 457–61. 1993. doi:10.1016/0039-128x(93)90002-5. PMID 8256254.
- ↑ "Estrogenic effects of the synthetic aminoestrogen 17 beta-(5-hydroxy-1-pentylamino)-1,3,5(10)-estratrien-3-ol (pentolame)". Steroids 63 (7–8): 433–8. 1998. doi:10.1016/s0039-128x(98)00046-4. PMID 9654651.
- ↑ "In vivo estrogen bioactivities and in vitro estrogen receptor binding and transcriptional activities of anticoagulant synthetic 17beta-aminoestrogens". J. Steroid Biochem. Mol. Biol. 73 (1–2): 59–66. 2000. doi:10.1016/s0960-0760(00)00053-4. PMID 10822025.
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